Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysis
Abstract Background Current evidence demonstrate that sugar-sweetened beverages (SSBs) and bone health are related; however, there has been only a few reviews on the link between SSBs and bone health. A systematic review and meta-analysis was performed to investigate the association between SSBs con...
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| Format: | Article |
| Language: | English |
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BMC
2021-05-01
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| Series: | Nutrition Journal |
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| Online Access: | https://doi.org/10.1186/s12937-021-00698-1 |
| _version_ | 1818943324655976448 |
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| author | Hyejin Ahn Yoo Kyoung Park |
| author_facet | Hyejin Ahn Yoo Kyoung Park |
| author_sort | Hyejin Ahn |
| collection | DOAJ |
| description | Abstract Background Current evidence demonstrate that sugar-sweetened beverages (SSBs) and bone health are related; however, there has been only a few reviews on the link between SSBs and bone health. A systematic review and meta-analysis was performed to investigate the association between SSBs consumption and bone health in chidren and adults. Methods Relevant studies of SSBs and bone health published up to 15 March 2021 were searched using PubMed, the Web of Science, Cochrane Library, and a reference search. A random-effects meta-analysis was conducted to estimate the standardized mean difference (SMD). Subgroup analyses were performed to identify whether effects were modified by age, sex, measured skeletal sites, type of SSBs, and SSBs intake questionnaire. Results Twenty-six publications including 124,691 participants were selected on the review. The results from this meta-analysis showed a significant inverse association between SSBs intake and bone mineral density (BMD) in adults (ES: -0.66, 95% CI: − 1.01, − 0.31, n = 4312). Eighteen of the 20 studies included in the qualitative-only review in children and adults supported the findings from the meta-analysis. When subgroup analysis was performed according to skeletal site, a large effect was found on whole body BMD (ES: -0.97, 95% CI: − 1.54, − 0.40). There was a moderate effect on BMD in females (ES: -0.50, 95% CI: − 0.87, − 0.13). There was a moderate or large effect on BMD in individuals aged under 50 years (under 30 years: ES: -0.57, 95% CI: − 0.97, − 0.17; 30 to 50 years: ES: -1.33, 95% CI: − 1.72, − 0.93). High consumption of carbonated beverages had a moderate effect on BMD (ES: -0.73, 95% CI: − 1.12, − 0.35). Conclusion The meta-analysis showed that SSBs consumption such as carbonated beverages were inversely related to BMD in adults. Qualitative review supported the results of meta-analysis. Trial registration This review was registered in the PROSPERO database under identifier CRD42020164428 . |
| first_indexed | 2024-12-20T07:25:31Z |
| format | Article |
| id | doaj.art-7e8dcccddcbc40a29801d6411c14f23f |
| institution | Directory Open Access Journal |
| issn | 1475-2891 |
| language | English |
| last_indexed | 2024-12-20T07:25:31Z |
| publishDate | 2021-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Nutrition Journal |
| spelling | doaj.art-7e8dcccddcbc40a29801d6411c14f23f2022-12-21T19:48:33ZengBMCNutrition Journal1475-28912021-05-0120111610.1186/s12937-021-00698-1Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysisHyejin Ahn0Yoo Kyoung Park1Department of Gerontology (AgeTech-Service Convergence Major), Kyung Hee UniversityDepartment of Medical Nutrition (AgeTech-Service Convergence Major), Graduate School of East-West Medical Science, Kyung Hee UniversityAbstract Background Current evidence demonstrate that sugar-sweetened beverages (SSBs) and bone health are related; however, there has been only a few reviews on the link between SSBs and bone health. A systematic review and meta-analysis was performed to investigate the association between SSBs consumption and bone health in chidren and adults. Methods Relevant studies of SSBs and bone health published up to 15 March 2021 were searched using PubMed, the Web of Science, Cochrane Library, and a reference search. A random-effects meta-analysis was conducted to estimate the standardized mean difference (SMD). Subgroup analyses were performed to identify whether effects were modified by age, sex, measured skeletal sites, type of SSBs, and SSBs intake questionnaire. Results Twenty-six publications including 124,691 participants were selected on the review. The results from this meta-analysis showed a significant inverse association between SSBs intake and bone mineral density (BMD) in adults (ES: -0.66, 95% CI: − 1.01, − 0.31, n = 4312). Eighteen of the 20 studies included in the qualitative-only review in children and adults supported the findings from the meta-analysis. When subgroup analysis was performed according to skeletal site, a large effect was found on whole body BMD (ES: -0.97, 95% CI: − 1.54, − 0.40). There was a moderate effect on BMD in females (ES: -0.50, 95% CI: − 0.87, − 0.13). There was a moderate or large effect on BMD in individuals aged under 50 years (under 30 years: ES: -0.57, 95% CI: − 0.97, − 0.17; 30 to 50 years: ES: -1.33, 95% CI: − 1.72, − 0.93). High consumption of carbonated beverages had a moderate effect on BMD (ES: -0.73, 95% CI: − 1.12, − 0.35). Conclusion The meta-analysis showed that SSBs consumption such as carbonated beverages were inversely related to BMD in adults. Qualitative review supported the results of meta-analysis. Trial registration This review was registered in the PROSPERO database under identifier CRD42020164428 .https://doi.org/10.1186/s12937-021-00698-1Meta-analysisSystematic reviewSugar-sweetened beveragesCarbonated beveragesBone healthBone mineral density |
| spellingShingle | Hyejin Ahn Yoo Kyoung Park Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysis Nutrition Journal Meta-analysis Systematic review Sugar-sweetened beverages Carbonated beverages Bone health Bone mineral density |
| title | Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysis |
| title_full | Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysis |
| title_fullStr | Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysis |
| title_full_unstemmed | Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysis |
| title_short | Sugar-sweetened beverage consumption and bone health: a systematic review and meta-analysis |
| title_sort | sugar sweetened beverage consumption and bone health a systematic review and meta analysis |
| topic | Meta-analysis Systematic review Sugar-sweetened beverages Carbonated beverages Bone health Bone mineral density |
| url | https://doi.org/10.1186/s12937-021-00698-1 |
| work_keys_str_mv | AT hyejinahn sugarsweetenedbeverageconsumptionandbonehealthasystematicreviewandmetaanalysis AT yookyoungpark sugarsweetenedbeverageconsumptionandbonehealthasystematicreviewandmetaanalysis |