What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study

<i>Background and Objectives:</i> This observational prospective study aims to examine the psychological and psychopathological impact of the pandemic stress on patients with pre-existing mood, anxiety and obsessive–compulsive disorders. <i>Materials and Methods:</i> The stud...

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Main Authors: Antonio Tundo, Sophia Betro’, Roberta Necci
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/57/4/304
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author Antonio Tundo
Sophia Betro’
Roberta Necci
author_facet Antonio Tundo
Sophia Betro’
Roberta Necci
author_sort Antonio Tundo
collection DOAJ
description <i>Background and Objectives:</i> This observational prospective study aims to examine the psychological and psychopathological impact of the pandemic stress on patients with pre-existing mood, anxiety and obsessive–compulsive disorders. <i>Materials and Methods:</i> The study includes 386 consecutive patients recruited from 10 March to 30 June 2020 among those being treated at the Institute of Psychopathology in Rome (Italy) with an age ≥18 years and meeting DSM-5 criteria for major depressive disorder (MDD) (35.2%), bipolar I (BD-I) (21.5%) or II (BD-II) (28.8%) disorder, obsessive–compulsive disorder (OCD) (7.5%), panic disorder (PD) (7.0%) or social anxiety (SA). A total of 34.2% had lifetime comorbid Axis I disorders and 15.3% had alcohol/drug abuse disorders. Using a semi-structured interview, we investigated if the impact of COVID-19 stress for patients has been similar, higher or lower than that of their family and friends and, for patients with relapse/symptoms worsening, if there was a relationship between the clinical condition worsening and the pandemic stress. <i>Results:</i> Compared with that experienced by their family members and friends, the psychological impact of pandemic stress was similar in 52.1% of the sample, better in 37.1% and worse in 10.8%. In 21 patients (5.4%), the stress triggered a recurrence or worsened the symptoms. Patients with OCD had a higher rate of worsening due to pandemic stress compared to patients with MDD (<i>p</i> = 0.033), although, overall, the χ<sup>2</sup> test was not significant among primary diagnoses (χ<sup>2</sup> = 8.368; <i>p</i> = 0.057). <i>Conclusions:</i> The psychological and psychopathological consequences of COVID-19 stress in our outpatients were very modest. The continuity of care offered during the lockdown could explain the results.
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spelling doaj.art-7e8e55ae8ad147e48b67f25fccf5d07e2023-11-21T11:47:26ZengMDPI AGMedicina1010-660X1648-91442021-03-0157430410.3390/medicina57040304What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective StudyAntonio Tundo0Sophia Betro’1Roberta Necci2Istituto di Psicopatologia, 00196 Rome, ItalyIstituto di Psicopatologia, 00196 Rome, ItalyIstituto di Psicopatologia, 00196 Rome, Italy<i>Background and Objectives:</i> This observational prospective study aims to examine the psychological and psychopathological impact of the pandemic stress on patients with pre-existing mood, anxiety and obsessive–compulsive disorders. <i>Materials and Methods:</i> The study includes 386 consecutive patients recruited from 10 March to 30 June 2020 among those being treated at the Institute of Psychopathology in Rome (Italy) with an age ≥18 years and meeting DSM-5 criteria for major depressive disorder (MDD) (35.2%), bipolar I (BD-I) (21.5%) or II (BD-II) (28.8%) disorder, obsessive–compulsive disorder (OCD) (7.5%), panic disorder (PD) (7.0%) or social anxiety (SA). A total of 34.2% had lifetime comorbid Axis I disorders and 15.3% had alcohol/drug abuse disorders. Using a semi-structured interview, we investigated if the impact of COVID-19 stress for patients has been similar, higher or lower than that of their family and friends and, for patients with relapse/symptoms worsening, if there was a relationship between the clinical condition worsening and the pandemic stress. <i>Results:</i> Compared with that experienced by their family members and friends, the psychological impact of pandemic stress was similar in 52.1% of the sample, better in 37.1% and worse in 10.8%. In 21 patients (5.4%), the stress triggered a recurrence or worsened the symptoms. Patients with OCD had a higher rate of worsening due to pandemic stress compared to patients with MDD (<i>p</i> = 0.033), although, overall, the χ<sup>2</sup> test was not significant among primary diagnoses (χ<sup>2</sup> = 8.368; <i>p</i> = 0.057). <i>Conclusions:</i> The psychological and psychopathological consequences of COVID-19 stress in our outpatients were very modest. The continuity of care offered during the lockdown could explain the results.https://www.mdpi.com/1648-9144/57/4/304coronaviruspanic disordersocial anxiety disordermajor depressive disorderbipolar disorderobsessive–compulsive disorder
spellingShingle Antonio Tundo
Sophia Betro’
Roberta Necci
What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study
Medicina
coronavirus
panic disorder
social anxiety disorder
major depressive disorder
bipolar disorder
obsessive–compulsive disorder
title What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study
title_full What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study
title_fullStr What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study
title_full_unstemmed What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study
title_short What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study
title_sort what is the impact of covid 19 pandemic on patients with pre existing mood or anxiety disorder an observational prospective study
topic coronavirus
panic disorder
social anxiety disorder
major depressive disorder
bipolar disorder
obsessive–compulsive disorder
url https://www.mdpi.com/1648-9144/57/4/304
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