Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study
Abstract To evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac joint (SIJ). The ossification and bridging of spinal ligament and fusion of the fac...
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-28946-w |
| _version_ | 1811171765661990912 |
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| author | Takuya Takahashi Toshitaka Yoshii Kanji Mori Shigeto Kobayashi Hisashi Inoue Kurisu Tada Naoto Tamura Takashi Hirai Nobuhiro Sugimura Narihito Nagoshi Satoshi Maki Keiichi Katsumi Masao Koda Kazuma Murata Kazuhiro Takeuchi Hiroaki Nakashima Shiro Imagama Yoshiharu Kawaguchi Masashi Yamazaki Atsushi Okawa |
| author_facet | Takuya Takahashi Toshitaka Yoshii Kanji Mori Shigeto Kobayashi Hisashi Inoue Kurisu Tada Naoto Tamura Takashi Hirai Nobuhiro Sugimura Narihito Nagoshi Satoshi Maki Keiichi Katsumi Masao Koda Kazuma Murata Kazuhiro Takeuchi Hiroaki Nakashima Shiro Imagama Yoshiharu Kawaguchi Masashi Yamazaki Atsushi Okawa |
| author_sort | Takuya Takahashi |
| collection | DOAJ |
| description | Abstract To evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac joint (SIJ). The ossification and bridging of spinal ligament and fusion of the facet joint and SIJ were evaluated in 111 patients who were diagnosed with DISH and 27 patients with AS on the whole spine CT. The number of anterior bridging and shape of bridging (candle-wax-type/ smooth-type) were also evaluated. We further evaluated patients with DISH and AS by matching their age and sex. Complete SIJ fusion was more common in AS, whereas anterior and posterior bony bridging around SIJ was more common in DISH. However, 63% of patients with DISH had a partial or complete fusion. In spinal anterior bony bridging, the majority of patients with AS had the smooth-type, whereas those with DISH had the candle-wax-type. However, some of the patients with DISH (11%) had smooth-type. Intervertebral facet joint fusion is more common in AS. The number of anterior spinal bony bridging was greater in AS than in DISH, especially in the lumbar spine. These results are useful in differentiating DISH from AS and should therefore be considered when making a diagnosis. |
| first_indexed | 2024-04-10T17:19:30Z |
| format | Article |
| id | doaj.art-7e8eb3ac4b76498a91a6c7f3cd79c088 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-10T17:19:30Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-7e8eb3ac4b76498a91a6c7f3cd79c0882023-02-05T12:10:08ZengNature PortfolioScientific Reports2045-23222023-02-011311910.1038/s41598-023-28946-wComparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter studyTakuya Takahashi0Toshitaka Yoshii1Kanji Mori2Shigeto Kobayashi3Hisashi Inoue4Kurisu Tada5Naoto Tamura6Takashi Hirai7Nobuhiro Sugimura8Narihito Nagoshi9Satoshi Maki10Keiichi Katsumi11Masao Koda12Kazuma Murata13Kazuhiro Takeuchi14Hiroaki Nakashima15Shiro Imagama16Yoshiharu Kawaguchi17Masashi Yamazaki18Atsushi Okawa19Department of Orthopedic Surgery, Tokyo Medical and Dental UniversityDepartment of Orthopedic Surgery, Tokyo Medical and Dental UniversityDepartment of Orthopedic Surgery, Shiga University of Medical ScienceDepartment of Internal Medicine, Juntendo University Koshigaya Hospital, Juntendo University School of MedicineDepartment of Orthopedic Surgery, Juntendo University School of MedicineDepartment of Internal Medicine and Rheumatology, Juntendo University School of MedicineDepartment of Internal Medicine and Rheumatology, Juntendo University School of MedicineDepartment of Orthopedic Surgery, Tokyo Medical and Dental UniversityTokyo Medical and Dental University School of MedicineDepartment of Orthopedic Surgery, School of Medicine, Keio UniversityDepartment of Orthopedic Surgery, Graduate School of Medicine, Chiba UniversityDepartment of Orthopedic Surgery, Niigata Central HospitalDepartment of Orthopedic Surgery, Faculty of Medicine, University of TsukubaDepartment of Orthopedic Surgery, Tokyo Medical UniversityDepartment of Orthopedic Surgery, National Hospital Organization Okayama Medical CenterDepartment of Orthopedic Surgery, Nagoya University Graduate School of MedicineDepartment of Orthopedic Surgery, Nagoya University Graduate School of MedicineDepartment of Orthopedic Surgery, Faculty of Medicine, University of ToyamaDepartment of Orthopedic Surgery, Faculty of Medicine, University of TsukubaDepartment of Orthopedic Surgery, Tokyo Medical and Dental UniversityAbstract To evaluate the radiological differences between diffuse idiopathic skeletal hyperostosis (DISH) and ankylosing spondylitis (AS) using whole spine computed tomography (CT), including the spine and sacroiliac joint (SIJ). The ossification and bridging of spinal ligament and fusion of the facet joint and SIJ were evaluated in 111 patients who were diagnosed with DISH and 27 patients with AS on the whole spine CT. The number of anterior bridging and shape of bridging (candle-wax-type/ smooth-type) were also evaluated. We further evaluated patients with DISH and AS by matching their age and sex. Complete SIJ fusion was more common in AS, whereas anterior and posterior bony bridging around SIJ was more common in DISH. However, 63% of patients with DISH had a partial or complete fusion. In spinal anterior bony bridging, the majority of patients with AS had the smooth-type, whereas those with DISH had the candle-wax-type. However, some of the patients with DISH (11%) had smooth-type. Intervertebral facet joint fusion is more common in AS. The number of anterior spinal bony bridging was greater in AS than in DISH, especially in the lumbar spine. These results are useful in differentiating DISH from AS and should therefore be considered when making a diagnosis.https://doi.org/10.1038/s41598-023-28946-w |
| spellingShingle | Takuya Takahashi Toshitaka Yoshii Kanji Mori Shigeto Kobayashi Hisashi Inoue Kurisu Tada Naoto Tamura Takashi Hirai Nobuhiro Sugimura Narihito Nagoshi Satoshi Maki Keiichi Katsumi Masao Koda Kazuma Murata Kazuhiro Takeuchi Hiroaki Nakashima Shiro Imagama Yoshiharu Kawaguchi Masashi Yamazaki Atsushi Okawa Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study Scientific Reports |
| title | Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study |
| title_full | Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study |
| title_fullStr | Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study |
| title_full_unstemmed | Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study |
| title_short | Comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: a multicenter study |
| title_sort | comparison of radiological characteristics between diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis a multicenter study |
| url | https://doi.org/10.1038/s41598-023-28946-w |
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