Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm.
Objectives: <i>Embelia ribes</i> Burm. (<i>E. ribes</i>, Myrsinaceae), also known as Vidanga in Ayurveda, has been shown to have significant therapeutic benefits on several disorders, and its main chemical bioactive constituent, embelin, has the therapeutic potential to be co...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/11/7/1359 |
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| author | Vineet Sharma Dev Nath Singh Gautam Andrei-Flavius Radu Tapan Behl Simona Gabriela Bungau Cosmin Mihai Vesa |
| author_facet | Vineet Sharma Dev Nath Singh Gautam Andrei-Flavius Radu Tapan Behl Simona Gabriela Bungau Cosmin Mihai Vesa |
| author_sort | Vineet Sharma |
| collection | DOAJ |
| description | Objectives: <i>Embelia ribes</i> Burm. (<i>E. ribes</i>, Myrsinaceae), also known as Vidanga in Ayurveda, has been shown to have significant therapeutic benefits on several disorders, and its main chemical bioactive constituent, embelin, has the therapeutic potential to be converted into innovative drugs, which is why it has recently received considerable interest. In the present work, we provide a higher level of comprehension, awareness, and extensive knowledge of the traditional uses, phytochemistry, and pharmacological characteristics of <i>E. ribes</i> throughout the last several decades (February 1965 to June 2021), emphasizing the importance of the study of essential oils extracted from <i>E. ribes</i>, which show a major potential for exerting antioxidant and anti-inflammatory activity. Materials and Methods: Google Scholar, MEDLINE, EMBASE, Scifinder, Scopus, and ScienceDirect were used to conduct a thorough literature search. Results: <i>E. ribes</i> is high in essential oils, alkaloids, flavonoids, steroids, and phenolics, all of which have medicinal benefits. The essential oils/extracts and isolated chemical constituents exhibited antioxidant activity, wound healing, antidiabetic, central nervous system (CNS)-related disease, antiviral, antiobesity, cardioprotective, antifungal, antibacterial, and antifertility activity, among other promising pharmacological effects. Conclusion: The translation between traditional applications and modern medicine may make <i>E. ribes</i> a promising target for the implementation of innovative medication. To investigate the efficacy and safety profile of <i>E. ribes</i>, further high-quality preclinical studies using advanced methodologies are required. |
| first_indexed | 2024-03-09T03:46:32Z |
| format | Article |
| id | doaj.art-7e91f9d705d04c3db0d32e87ff1cb27d |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-09T03:46:32Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-7e91f9d705d04c3db0d32e87ff1cb27d2023-12-03T14:34:10ZengMDPI AGAntioxidants2076-39212022-07-01117135910.3390/antiox11071359Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm.Vineet Sharma0Dev Nath Singh Gautam1Andrei-Flavius Radu2Tapan Behl3Simona Gabriela Bungau4Cosmin Mihai Vesa5Department of Rasa Shastra & Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, IndiaDepartment of Rasa Shastra & Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, IndiaDoctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, IndiaDoctoral School of Biomedical Sciences, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaDepartment of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, RomaniaObjectives: <i>Embelia ribes</i> Burm. (<i>E. ribes</i>, Myrsinaceae), also known as Vidanga in Ayurveda, has been shown to have significant therapeutic benefits on several disorders, and its main chemical bioactive constituent, embelin, has the therapeutic potential to be converted into innovative drugs, which is why it has recently received considerable interest. In the present work, we provide a higher level of comprehension, awareness, and extensive knowledge of the traditional uses, phytochemistry, and pharmacological characteristics of <i>E. ribes</i> throughout the last several decades (February 1965 to June 2021), emphasizing the importance of the study of essential oils extracted from <i>E. ribes</i>, which show a major potential for exerting antioxidant and anti-inflammatory activity. Materials and Methods: Google Scholar, MEDLINE, EMBASE, Scifinder, Scopus, and ScienceDirect were used to conduct a thorough literature search. Results: <i>E. ribes</i> is high in essential oils, alkaloids, flavonoids, steroids, and phenolics, all of which have medicinal benefits. The essential oils/extracts and isolated chemical constituents exhibited antioxidant activity, wound healing, antidiabetic, central nervous system (CNS)-related disease, antiviral, antiobesity, cardioprotective, antifungal, antibacterial, and antifertility activity, among other promising pharmacological effects. Conclusion: The translation between traditional applications and modern medicine may make <i>E. ribes</i> a promising target for the implementation of innovative medication. To investigate the efficacy and safety profile of <i>E. ribes</i>, further high-quality preclinical studies using advanced methodologies are required.https://www.mdpi.com/2076-3921/11/7/1359<i>Embelia ribes</i> Burm.Vidangaantioxidantsessential oils/extractsembelinvilangin |
| spellingShingle | Vineet Sharma Dev Nath Singh Gautam Andrei-Flavius Radu Tapan Behl Simona Gabriela Bungau Cosmin Mihai Vesa Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm. Antioxidants <i>Embelia ribes</i> Burm. Vidanga antioxidants essential oils/extracts embelin vilangin |
| title | Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm. |
| title_full | Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm. |
| title_fullStr | Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm. |
| title_full_unstemmed | Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm. |
| title_short | Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of <i>Embelia ribes</i> Burm. |
| title_sort | reviewing the traditional modern uses phytochemistry essential oils extracts and pharmacology of i embelia ribes i burm |
| topic | <i>Embelia ribes</i> Burm. Vidanga antioxidants essential oils/extracts embelin vilangin |
| url | https://www.mdpi.com/2076-3921/11/7/1359 |
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