Doxorubicin‐loaded nanoparticle coated with endothelial cells‐derived exosomes for immunogenic chemotherapy of glioblastoma

Doxorubicin‐loaded nanoparticle coated with endothelial cells‐derived exosomes for immunogenic chemotherapy of glioblastoma

Abstract Treatments of glioblastoma (GBM) have not been very effective, largely due to the inefficiency of drugs in penetrating the blood brain barrier (BBB). In this study, we investigated the potential of exosome‐coated doxorubicin (DOX)‐loaded nanoparticles (ENPDOX) in BBB penetration, inducing i...

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Bibliographic Details
Main Authors: Chao Zhang, Jian Song, Lei Lou, Xuejiao Qi, Lei Zhao, Bo Fan, Guozhu Sun, Zhongqiang Lv, Zhenzeng Fan, Baohua Jiao, Jiankai Yang
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Bioengineering & Translational Medicine
Subjects:
blood brain barrier
doxorubicin
exosome‐coated doxorubicin‐loaded nanoparticle
glioblastoma
immunogenic cell death
Online Access:https://doi.org/10.1002/btm2.10203

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