Catechol-O-methyltransferase Val158Met polymorphism is associated with somatosensory amplification and nocebo responses.

Catechol-O-methyltransferase Val158Met polymorphism is associated with somatosensory amplification and nocebo responses.

A large number of unwanted adverse events and symptoms reported by patients in clinical trials are not caused by the drug provided, since most of adverse events also occur in corresponding placebo groups. These nocebo effects also play a major role in drug discontinuation in clinical practice, negat...

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Hlavní autoři: Laura Wendt, Antje Albring, Sven Benson, Harald Engler, Andrea Engler, Anke Hinney, Winfried Rief, Oliver Witzke, Manfred Schedlowski
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4164653?pdf=render

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