Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri
This research presents the results of investigation of laser polarization fluorescence of biological layers (histological sections, cytological smears) in the task of diagnostics and differentiation of early stages of cancer: Dysplasia — cervical microinvasive carcinoma of cervix uteri. The analytic...
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| Format: | Article |
| Language: | English |
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World Scientific Publishing
2014-05-01
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| Series: | Journal of Innovative Optical Health Sciences |
| Subjects: | |
| Online Access: | http://www.worldscientific.com/doi/pdf/10.1142/S1793545814500242 |
| _version_ | 1828532354586509312 |
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| author | Yu. A. Ushenko M. I. Sidor N. Pashkovskaia G. D. Koval Yu. F. Marchuk D. Andreichuk |
| author_facet | Yu. A. Ushenko M. I. Sidor N. Pashkovskaia G. D. Koval Yu. F. Marchuk D. Andreichuk |
| author_sort | Yu. A. Ushenko |
| collection | DOAJ |
| description | This research presents the results of investigation of laser polarization fluorescence of biological layers (histological sections, cytological smears) in the task of diagnostics and differentiation of early stages of cancer: Dysplasia — cervical microinvasive carcinoma of cervix uteri. The analytical conditions of polarization-optimal probing of biological layers were determined basing on the model of linear birefringence and dichroism of birefringent (fibrillar, porphyrin) networks. The technique of polarization-variable laser autofluorescence was developed and experimentally tested. The objective criteria (statistical moments) of differentiation of histological sections autofluorescent images of endometrium biopsy and cytological smears of it mucous coat were defined. The operational characteristics (sensitivity, specificity, accuracy) of this technique were determined concerning the positions of probative medicine, and clinical efficiency. |
| first_indexed | 2024-12-11T22:51:00Z |
| format | Article |
| id | doaj.art-7e976c8d5d6844f3a3baf2e6aa825fe4 |
| institution | Directory Open Access Journal |
| issn | 1793-5458 1793-7205 |
| language | English |
| last_indexed | 2024-12-11T22:51:00Z |
| publishDate | 2014-05-01 |
| publisher | World Scientific Publishing |
| record_format | Article |
| series | Journal of Innovative Optical Health Sciences |
| spelling | doaj.art-7e976c8d5d6844f3a3baf2e6aa825fe42022-12-22T00:47:26ZengWorld Scientific PublishingJournal of Innovative Optical Health Sciences1793-54581793-72052014-05-01731450024-11450024-1010.1142/S179354581450024210.1142/S1793545814500242Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteriYu. A. Ushenko0M. I. Sidor1N. Pashkovskaia2G. D. Koval3Yu. F. Marchuk4D. Andreichuk5Correlation Optics Department, Chernivtsi National University, 2 Kotsyubinsky Street, Chernivtsi 58012, UkraineCorrelation Optics Department, Chernivtsi National University, 2 Kotsyubinsky Street, Chernivtsi 58012, UkraineClinical Immunology, Allergology and Endocrinology Department, Bucovinian State Medical University, 2 Theatral Sq., Chernivtsi 58002, UkraineClinical Immunology, Allergology and Endocrinology Department, Bucovinian State Medical University, 2 Theatral Sq., Chernivtsi 58002, UkraineClinical Immunology, Allergology and Endocrinology Department, Bucovinian State Medical University, 2 Theatral Sq., Chernivtsi 58002, UkraineClinical Immunology, Allergology and Endocrinology Department, Bucovinian State Medical University, 2 Theatral Sq., Chernivtsi 58002, UkraineThis research presents the results of investigation of laser polarization fluorescence of biological layers (histological sections, cytological smears) in the task of diagnostics and differentiation of early stages of cancer: Dysplasia — cervical microinvasive carcinoma of cervix uteri. The analytical conditions of polarization-optimal probing of biological layers were determined basing on the model of linear birefringence and dichroism of birefringent (fibrillar, porphyrin) networks. The technique of polarization-variable laser autofluorescence was developed and experimentally tested. The objective criteria (statistical moments) of differentiation of histological sections autofluorescent images of endometrium biopsy and cytological smears of it mucous coat were defined. The operational characteristics (sensitivity, specificity, accuracy) of this technique were determined concerning the positions of probative medicine, and clinical efficiency.http://www.worldscientific.com/doi/pdf/10.1142/S1793545814500242Autofluorescencepolarizationbirefringencestatistical opticsdiagnosticsmedical and autofluorescence imaging |
| spellingShingle | Yu. A. Ushenko M. I. Sidor N. Pashkovskaia G. D. Koval Yu. F. Marchuk D. Andreichuk Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri Journal of Innovative Optical Health Sciences Autofluorescence polarization birefringence statistical optics diagnostics medical and autofluorescence imaging |
| title | Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri |
| title_full | Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri |
| title_fullStr | Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri |
| title_full_unstemmed | Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri |
| title_short | Laser polarization-variable autofluorescence of the network of optically anisotropic biological tissues: Diagnostics and differentiation of early stages of cancer of cervix uteri |
| title_sort | laser polarization variable autofluorescence of the network of optically anisotropic biological tissues diagnostics and differentiation of early stages of cancer of cervix uteri |
| topic | Autofluorescence polarization birefringence statistical optics diagnostics medical and autofluorescence imaging |
| url | http://www.worldscientific.com/doi/pdf/10.1142/S1793545814500242 |
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