Rapid multi-locus sequence typing using microfluidic biochips.

Rapid multi-locus sequence typing using microfluidic biochips.

Multiple locus sequence typing (MLST) has become a central genotyping strategy for analysis of bacterial populations. The scheme involves de novo sequencing of 6-8 housekeeping loci to assign unique sequence types. In this work we adapted MLST to a rapid microfluidics platform in order to enhance sp...

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Bibliographic Details
Main Authors: Timothy D Read, Rosemary S Turingan, Christopher Cook, Heidi Giese, Ulrich Hans Thomann, Catherine C Hogan, Eugene Tan, Richard F Selden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2868872?pdf=render

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