Probing the Structures of Viral RNA Regulatory Elements with SHAPE and Related Methodologies

Probing the Structures of Viral RNA Regulatory Elements with SHAPE and Related Methodologies

Viral RNAs were selected by evolution to possess maximum functionality in a minimal sequence. Depending on the classification of the virus and the type of RNA in question, viral RNAs must alternately be replicated, spliced, transcribed, transported from the nucleus into the cytoplasm, translated and...

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Bibliographic Details
Main Authors: Jason W. Rausch, Joanna Sztuba-Solinska, Stuart F. J. Le Grice
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Microbiology
Subjects:
SHAPE
RNA structure
secondary structure
chemical probing
viral RNA
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02634/full

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