Glyceraldehyde-3-phosphate Dehydrogenase Is a Multifaceted Therapeutic Target
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme whose role in cell metabolism and homeostasis is well defined, while its function in pathologic processes needs further elucidation. Depending on the cell context, GAPDH may bind a number of physiologically important proteins, c...
Main Authors: | Vladimir F. Lazarev, Irina V. Guzhova, Boris A. Margulis |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
|
Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/12/5/416 |
Similar Items
-
The role of sperm-specific glyceraldehyde-3-phosphate dehydrogenase in the development of pathologies—from asthenozoospermia to carcinogenesis
by: Irina Naletova, et al.
Published: (2023-08-01) -
Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors
by: Robert Mandic, et al.
Published: (2020-04-01) -
Glyceraldehyde-3-phosphate dehydrogenase is overexpressed in colorectal cancer onset
by: Míriam Tarrado-Castellarnau, et al.
Published: (2017-06-01) -
Interactome of Glyceraldehyde-3-Phosphate Dehydrogenase Points to the Existence of Metabolons in Paracoccidioides lutzii
by: Kleber Santiago Freitas e Silva, et al.
Published: (2019-07-01) -
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase enhances formation of the blood-clot lysis protein plasmin
by: David B. Pirovich, et al.
Published: (2020-03-01)