Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes

Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes

In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes. Miltefosine induced a process of programmed cell death, which was determined by the externalization of...

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Bibliographic Details
Main Authors: Fernanda de Aquino Marinho, Keyla Cristiny da Silva Gonçalves, Selma Soares de Oliveira, Ana-Carolina de Siqueira Couto de Oliveira, Maria Bellio, Claudia Masini d'Avila-Levy, André Luis Souza dos Santos, Marta Helena Branquinha
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2011-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
leishmaniasis
chemotherapy
apoptosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000400021&lng=en&tlng=en

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