OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection

Abstract The intestinal epithelium is a single cell layer that is constantly renewed and acts as a physical barrier that separates intestinal microbiota from underlying tissues. In inflammatory bowel disease (IBD) in humans, as well as in experimental mouse models of IBD, this barrier is impaired, c...

Full description

Bibliographic Details
Main Authors: Lien Verboom, Christopher J. Anderson, Maude Jans, Ioanna Petta, Gillian Blancke, Arne Martens, Mozes Sze, Tino Hochepied, Kodi S. Ravichandran, Lars Vereecke, Geert van Loo
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06058-7

Internet

https://doi.org/10.1038/s41419-023-06058-7

Similar Items