Development of a Highly Sensitive Neurofilament Light Chain Assay on an Automated Immunoassay Platform

Development of a Highly Sensitive Neurofilament Light Chain Assay on an Automated Immunoassay Platform

BackgroundNeurofilament light chain (NfL) is an axonal cytoskeletal protein that is released into the extracellular space following neuronal or axonal injury associated with neurological conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and other diseases. NfL is detec...

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Bibliographic Details
Main Authors:	Stephen Lee, Tatiana Plavina, Carol M. Singh, Kuangnan Xiong, Xiaolei Qiu, Richard A. Rudick, Peter A. Calabresi, Lauren Stevenson, Danielle Graham, Denitza Raitcheva, Christopher Green, Madeleine Matias, Arejas J. Uzgiris
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Neurology
Subjects:	assay neurofilament biomarker neurodegenerative article type: original research manuscript section multiple sclerosis amyotrophic lateral sclerosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2022.935382/full

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