Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection

Immune evasion by proteolytic shedding of natural killer group 2, member D ligands in Helicobacter pylori infection

BackgroundHelicobacter pylori (H. pylori) uses various strategies that attenuate mucosal immunity to ensure its persistence in the stomach. We recently found evidence that H. pylori might modulate the natural killer group 2, member 2 (NKG2D) system. The NKG2D receptor and its ligands are a major act...

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Bibliographic Details
Main Authors: Margit Anthofer, Markus Windisch, Rosa Haller, Sandra Ehmann, Sebastian Wrighton, Michael Miller, Lorenz Schernthanner, Iris Kufferath, Silvia Schauer, Barbara Jelušić, Sabine Kienesberger, Ellen L. Zechner, Gernot Posselt, Mar Vales-Gomez, Hugh T. Reyburn, Gregor Gorkiewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
H. pylori
immune evasion
NK cells
cytotoxic T cells
stomach cancer
tumor immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1282680/full

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