Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan

Bisphenol-A (BPA) is defined as one of the endocrine disrupting compounds. The accurate and inexpensive colorimetric paper-based analytical devices (PADs) are of crucial importance for BPA analysis. In this context, we developed for the first time a new PAD modified with chitosan and sulfamethoxazol...

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Main Authors: Abdelhafid Karrat, Aziz Amine
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/10/11/450
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author Abdelhafid Karrat
Aziz Amine
author_facet Abdelhafid Karrat
Aziz Amine
author_sort Abdelhafid Karrat
collection DOAJ
description Bisphenol-A (BPA) is defined as one of the endocrine disrupting compounds. The accurate and inexpensive colorimetric paper-based analytical devices (PADs) are of crucial importance for BPA analysis. In this context, we developed for the first time a new PAD modified with chitosan and sulfamethoxazole (Chitosan-PAD) for the visual detection of BPA in water. The PAD was characterized by Fourier-transform infrared spectroscopy, which confirmed its modification by the functionalized chitosan. A yellow coloration was developed when a small volume of BPA was added to the Chitosan-PAD, allowing for visual and smartphone detection. This new strategy is based on a specific combination of BPA with chitosan and sulfamethoxazole that provides a hight selectivity to the Chitosan-PAD. The proposed PAD was successfully employed in combination with a pre-concentration step for the detection of 0.01 µg mL<sup>−1</sup> of PBA with the naked eye using a 10-fold preconcentration factor. The PAD was effectively applied for BPA quantification in water samples with good recoveries. The developed PAD provides a green and cost-effective strategy for the on-site and one-step detection of BPA in water samples.
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spelling doaj.art-7eb7f24b5f274977bfb26140e7606ee52023-11-24T04:10:25ZengMDPI AGChemosensors2227-90402022-10-01101145010.3390/chemosensors10110450Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized ChitosanAbdelhafid Karrat0Aziz Amine1Laboratory of Process Engineering and Environment, Faculty of Sciences and Techniques, Hassan II University of Casablanca, P.A. 146., Mohammedia 28806, MoroccoLaboratory of Process Engineering and Environment, Faculty of Sciences and Techniques, Hassan II University of Casablanca, P.A. 146., Mohammedia 28806, MoroccoBisphenol-A (BPA) is defined as one of the endocrine disrupting compounds. The accurate and inexpensive colorimetric paper-based analytical devices (PADs) are of crucial importance for BPA analysis. In this context, we developed for the first time a new PAD modified with chitosan and sulfamethoxazole (Chitosan-PAD) for the visual detection of BPA in water. The PAD was characterized by Fourier-transform infrared spectroscopy, which confirmed its modification by the functionalized chitosan. A yellow coloration was developed when a small volume of BPA was added to the Chitosan-PAD, allowing for visual and smartphone detection. This new strategy is based on a specific combination of BPA with chitosan and sulfamethoxazole that provides a hight selectivity to the Chitosan-PAD. The proposed PAD was successfully employed in combination with a pre-concentration step for the detection of 0.01 µg mL<sup>−1</sup> of PBA with the naked eye using a 10-fold preconcentration factor. The PAD was effectively applied for BPA quantification in water samples with good recoveries. The developed PAD provides a green and cost-effective strategy for the on-site and one-step detection of BPA in water samples.https://www.mdpi.com/2227-9040/10/11/450chitosansmartphonepaper-based analytical devicesone-step detectionbisphenol-A
spellingShingle Abdelhafid Karrat
Aziz Amine
Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan
Chemosensors
chitosan
smartphone
paper-based analytical devices
one-step detection
bisphenol-A
title Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan
title_full Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan
title_fullStr Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan
title_full_unstemmed Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan
title_short Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan
title_sort paper based analytical device for one step detection of bisphenol a using functionalized chitosan
topic chitosan
smartphone
paper-based analytical devices
one-step detection
bisphenol-A
url https://www.mdpi.com/2227-9040/10/11/450
work_keys_str_mv AT abdelhafidkarrat paperbasedanalyticaldeviceforonestepdetectionofbisphenolausingfunctionalizedchitosan
AT azizamine paperbasedanalyticaldeviceforonestepdetectionofbisphenolausingfunctionalizedchitosan