Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan
Bisphenol-A (BPA) is defined as one of the endocrine disrupting compounds. The accurate and inexpensive colorimetric paper-based analytical devices (PADs) are of crucial importance for BPA analysis. In this context, we developed for the first time a new PAD modified with chitosan and sulfamethoxazol...
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MDPI AG
2022-10-01
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Series: | Chemosensors |
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Online Access: | https://www.mdpi.com/2227-9040/10/11/450 |
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author | Abdelhafid Karrat Aziz Amine |
author_facet | Abdelhafid Karrat Aziz Amine |
author_sort | Abdelhafid Karrat |
collection | DOAJ |
description | Bisphenol-A (BPA) is defined as one of the endocrine disrupting compounds. The accurate and inexpensive colorimetric paper-based analytical devices (PADs) are of crucial importance for BPA analysis. In this context, we developed for the first time a new PAD modified with chitosan and sulfamethoxazole (Chitosan-PAD) for the visual detection of BPA in water. The PAD was characterized by Fourier-transform infrared spectroscopy, which confirmed its modification by the functionalized chitosan. A yellow coloration was developed when a small volume of BPA was added to the Chitosan-PAD, allowing for visual and smartphone detection. This new strategy is based on a specific combination of BPA with chitosan and sulfamethoxazole that provides a hight selectivity to the Chitosan-PAD. The proposed PAD was successfully employed in combination with a pre-concentration step for the detection of 0.01 µg mL<sup>−1</sup> of PBA with the naked eye using a 10-fold preconcentration factor. The PAD was effectively applied for BPA quantification in water samples with good recoveries. The developed PAD provides a green and cost-effective strategy for the on-site and one-step detection of BPA in water samples. |
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issn | 2227-9040 |
language | English |
last_indexed | 2024-03-09T19:10:57Z |
publishDate | 2022-10-01 |
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spelling | doaj.art-7eb7f24b5f274977bfb26140e7606ee52023-11-24T04:10:25ZengMDPI AGChemosensors2227-90402022-10-01101145010.3390/chemosensors10110450Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized ChitosanAbdelhafid Karrat0Aziz Amine1Laboratory of Process Engineering and Environment, Faculty of Sciences and Techniques, Hassan II University of Casablanca, P.A. 146., Mohammedia 28806, MoroccoLaboratory of Process Engineering and Environment, Faculty of Sciences and Techniques, Hassan II University of Casablanca, P.A. 146., Mohammedia 28806, MoroccoBisphenol-A (BPA) is defined as one of the endocrine disrupting compounds. The accurate and inexpensive colorimetric paper-based analytical devices (PADs) are of crucial importance for BPA analysis. In this context, we developed for the first time a new PAD modified with chitosan and sulfamethoxazole (Chitosan-PAD) for the visual detection of BPA in water. The PAD was characterized by Fourier-transform infrared spectroscopy, which confirmed its modification by the functionalized chitosan. A yellow coloration was developed when a small volume of BPA was added to the Chitosan-PAD, allowing for visual and smartphone detection. This new strategy is based on a specific combination of BPA with chitosan and sulfamethoxazole that provides a hight selectivity to the Chitosan-PAD. The proposed PAD was successfully employed in combination with a pre-concentration step for the detection of 0.01 µg mL<sup>−1</sup> of PBA with the naked eye using a 10-fold preconcentration factor. The PAD was effectively applied for BPA quantification in water samples with good recoveries. The developed PAD provides a green and cost-effective strategy for the on-site and one-step detection of BPA in water samples.https://www.mdpi.com/2227-9040/10/11/450chitosansmartphonepaper-based analytical devicesone-step detectionbisphenol-A |
spellingShingle | Abdelhafid Karrat Aziz Amine Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan Chemosensors chitosan smartphone paper-based analytical devices one-step detection bisphenol-A |
title | Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan |
title_full | Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan |
title_fullStr | Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan |
title_full_unstemmed | Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan |
title_short | Paper-Based Analytical Device for One-Step Detection of Bisphenol-A Using Functionalized Chitosan |
title_sort | paper based analytical device for one step detection of bisphenol a using functionalized chitosan |
topic | chitosan smartphone paper-based analytical devices one-step detection bisphenol-A |
url | https://www.mdpi.com/2227-9040/10/11/450 |
work_keys_str_mv | AT abdelhafidkarrat paperbasedanalyticaldeviceforonestepdetectionofbisphenolausingfunctionalizedchitosan AT azizamine paperbasedanalyticaldeviceforonestepdetectionofbisphenolausingfunctionalizedchitosan |