Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-Analysis
Mild cognitive impairment (MCI), a neurodegenerative disease leading to Alzheimer’s disease or dementia, is often associated with physical complaints. Combined physical and cognitive training (PCT) has been investigated to see the effects on cognitive function, but its impact on motor functions and...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/2/276 |
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| author | Pawel Kiper Michelle Richard Françoise Stefanutti Romain Pierson-Poinsignon Luisa Cacciante Cecilia Perin Miryam Mazzucchelli Barbara Viganò Roberto Meroni |
| author_facet | Pawel Kiper Michelle Richard Françoise Stefanutti Romain Pierson-Poinsignon Luisa Cacciante Cecilia Perin Miryam Mazzucchelli Barbara Viganò Roberto Meroni |
| author_sort | Pawel Kiper |
| collection | DOAJ |
| description | Mild cognitive impairment (MCI), a neurodegenerative disease leading to Alzheimer’s disease or dementia, is often associated with physical complaints. Combined physical and cognitive training (PCT) has been investigated to see the effects on cognitive function, but its impact on motor functions and activities of daily living has not been explored yet. The combination of physical and cognitive training may be a valuable non-pharmacological intervention that could preserve motor function and quality of life (QoL). We aimed, therefore, to analyze if combined PCT is effective at improving motor performance in patients with an MCI. A systematic electronic literature search and a meta-analysis were conducted. The following criteria were compulsory for inclusion in the study: (1) randomized controlled trial design; (2) combined PCT compared to motor training alone or no intervention; (3) motor outcomes as a study’s end point. Nine articles met the inclusion criteria. Results showed that PCT significantly enhances balance compared to motor training alone (SMD 0.56; 95% CI 0.07 to 1.06; I<sup>2</sup> = 59%; 160 participants), whereas a significant improvement was found for mobility in the PCT group when compared to no intervention (MD −1.80; 95% CI −2.70 to −0.90; I<sup>2</sup> = 0%; 81 participants). However, there is no evidence that people with MCI experience an increase in gait speed and QoL at the end of their practice sessions. Further investigation with larger samples and a longer period of monitoring after intervention should be undertaken. |
| first_indexed | 2024-03-09T21:37:23Z |
| format | Article |
| id | doaj.art-7ebbc0cae4734c44b126828e7b811a70 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T21:37:23Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-7ebbc0cae4734c44b126828e7b811a702023-11-23T20:40:54ZengMDPI AGJournal of Personalized Medicine2075-44262022-02-0112227610.3390/jpm12020276Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-AnalysisPawel Kiper0Michelle Richard1Françoise Stefanutti2Romain Pierson-Poinsignon3Luisa Cacciante4Cecilia Perin5Miryam Mazzucchelli6Barbara Viganò7Roberto Meroni8Physical Medicine and Rehabilitation Unit, Azienda ULSS 3 Serenissima, 30126 Venice, ItalyDepartment of Physiotherapy, LUNEX International University of Health Exercise and Sports, L-4671 Differdange, LuxembourgDepartment of Physiotherapy, LUNEX International University of Health Exercise and Sports, L-4671 Differdange, LuxembourgDepartment of Physiotherapy, LUNEX International University of Health Exercise and Sports, L-4671 Differdange, LuxembourgLaboratory of Rehabilitation Technologies, IRCCS San Camillo Hospital, 30126 Venice, ItalySchool of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, ItalySchool of Medicine and Surgery, University of Milano-Bicocca, 20126 Milan, ItalyGDS Foundation, 20841 Carate Brianza, ItalyDepartment of Physiotherapy, LUNEX International University of Health Exercise and Sports, L-4671 Differdange, LuxembourgMild cognitive impairment (MCI), a neurodegenerative disease leading to Alzheimer’s disease or dementia, is often associated with physical complaints. Combined physical and cognitive training (PCT) has been investigated to see the effects on cognitive function, but its impact on motor functions and activities of daily living has not been explored yet. The combination of physical and cognitive training may be a valuable non-pharmacological intervention that could preserve motor function and quality of life (QoL). We aimed, therefore, to analyze if combined PCT is effective at improving motor performance in patients with an MCI. A systematic electronic literature search and a meta-analysis were conducted. The following criteria were compulsory for inclusion in the study: (1) randomized controlled trial design; (2) combined PCT compared to motor training alone or no intervention; (3) motor outcomes as a study’s end point. Nine articles met the inclusion criteria. Results showed that PCT significantly enhances balance compared to motor training alone (SMD 0.56; 95% CI 0.07 to 1.06; I<sup>2</sup> = 59%; 160 participants), whereas a significant improvement was found for mobility in the PCT group when compared to no intervention (MD −1.80; 95% CI −2.70 to −0.90; I<sup>2</sup> = 0%; 81 participants). However, there is no evidence that people with MCI experience an increase in gait speed and QoL at the end of their practice sessions. Further investigation with larger samples and a longer period of monitoring after intervention should be undertaken.https://www.mdpi.com/2075-4426/12/2/276MCIcombined trainingmotor and cognitive trainingmotor performance |
| spellingShingle | Pawel Kiper Michelle Richard Françoise Stefanutti Romain Pierson-Poinsignon Luisa Cacciante Cecilia Perin Miryam Mazzucchelli Barbara Viganò Roberto Meroni Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-Analysis Journal of Personalized Medicine MCI combined training motor and cognitive training motor performance |
| title | Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-Analysis |
| title_full | Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-Analysis |
| title_fullStr | Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-Analysis |
| title_full_unstemmed | Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-Analysis |
| title_short | Combined Motor and Cognitive Rehabilitation: The Impact on Motor Performance in Patients with Mild Cognitive Impairment. Systematic Review and Meta-Analysis |
| title_sort | combined motor and cognitive rehabilitation the impact on motor performance in patients with mild cognitive impairment systematic review and meta analysis |
| topic | MCI combined training motor and cognitive training motor performance |
| url | https://www.mdpi.com/2075-4426/12/2/276 |
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