Role of IL-33-ST2 pathway in regulating inflammation: current evidence and future perspectives

Role of IL-33-ST2 pathway in regulating inflammation: current evidence and future perspectives

Abstract Interleukin (IL)-33 is an alarmin of the IL-1 superfamily localized to the nucleus of expressing cells, such as endothelial cells, epithelial cells, and fibroblasts. In response to cellular damage or stress, IL-33 is released and activates innate immune responses in some immune and structur...

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Bibliographic Details
Main Authors: Yilu Zhou, Zhendong Xu, Zhiqiang Liu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Translational Medicine
Subjects:
IL-33
Sepsis
Asthma
Inflammation
Inflammatory response
Online Access:https://doi.org/10.1186/s12967-023-04782-4

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