FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury

FOXO1 reshapes neutrophils to aggravate acute brain damage and promote late depression after traumatic brain injury

Abstract Background Neutrophils are traditionally viewed as first responders but have a short onset of action in response to traumatic brain injury (TBI). However, the heterogeneity, multifunctionality, and time-dependent modulation of brain damage and outcome mediated by neutrophils after TBI remai...

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Bibliographic Details
Main Authors: Mi Zhou, Yang-Wu-Yue Liu, Yu-Hang He, Jing-Yu Zhang, Hao Guo, Hao Wang, Jia-Kui Ren, Yi-Xun Su, Teng Yang, Jia-Bo Li, Wen-Hui He, Peng-Jiao Ma, Man-Tian Mi, Shuang-Shuang Dai
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Military Medical Research
Subjects:
Traumatic brain injury (TBI)
Neutrophil
Forkhead box protein O1 (FOXO1)
Acute stage
Chronic stage
Online Access:https://doi.org/10.1186/s40779-024-00523-w

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