Biomarkers for Primary Sjögren’s Syndrome
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninva...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-08-01
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| Series: | Genomics, Proteomics & Bioinformatics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1672022915001059 |
| _version_ | 1797330691917086720 |
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| author | Weiqian Chen Heng Cao Jin Lin Nancy Olsen Song Guo Zheng |
| author_facet | Weiqian Chen Heng Cao Jin Lin Nancy Olsen Song Guo Zheng |
| author_sort | Weiqian Chen |
| collection | DOAJ |
| description | Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions. |
| first_indexed | 2024-03-08T07:23:22Z |
| format | Article |
| id | doaj.art-7ec084b4812d4b8f9fcd223061649686 |
| institution | Directory Open Access Journal |
| issn | 1672-0229 |
| language | English |
| last_indexed | 2024-03-08T07:23:22Z |
| publishDate | 2015-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Genomics, Proteomics & Bioinformatics |
| spelling | doaj.art-7ec084b4812d4b8f9fcd2230616496862024-02-02T22:33:42ZengElsevierGenomics, Proteomics & Bioinformatics1672-02292015-08-0113421922310.1016/j.gpb.2015.06.002Biomarkers for Primary Sjögren’s SyndromeWeiqian Chen0Heng Cao1Jin Lin2Nancy Olsen3Song Guo Zheng4Division of Rheumatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, ChinaDivision of Rheumatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, ChinaDivision of Rheumatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, ChinaDivision of Rheumatology, Penn State University Hershey College of Medicine, Hershey, PA 17033, USADivision of Rheumatology, Penn State University Hershey College of Medicine, Hershey, PA 17033, USAPrimary Sjögren’s syndrome (pSS) is a systemic autoimmune disease with exocrine gland dysfunction and multi-organ involvement. Recent progress in understanding the pathogenesis of pSS offers an opportunity to find new biomarkers for the diagnosis and assessment of disease activity. Screening noninvasive biomarkers from the saliva and tears has significant potential. The need for specific and sensitive biomarker candidates in pSS is significant. This review aims to summarize recent advances in the identification of biomarkers of Sjögren syndrome, trying to identify reliable, sensitive, and specific biomarkers that can be used to guide treatment decisions.http://www.sciencedirect.com/science/article/pii/S1672022915001059BiomarkerFms-like tyrosine kinase 3 ligandMyxovirus-resistance protein ANon-coding RNAsSalivaSjögren syndrome |
| spellingShingle | Weiqian Chen Heng Cao Jin Lin Nancy Olsen Song Guo Zheng Biomarkers for Primary Sjögren’s Syndrome Genomics, Proteomics & Bioinformatics Biomarker Fms-like tyrosine kinase 3 ligand Myxovirus-resistance protein A Non-coding RNAs Saliva Sjögren syndrome |
| title | Biomarkers for Primary Sjögren’s Syndrome |
| title_full | Biomarkers for Primary Sjögren’s Syndrome |
| title_fullStr | Biomarkers for Primary Sjögren’s Syndrome |
| title_full_unstemmed | Biomarkers for Primary Sjögren’s Syndrome |
| title_short | Biomarkers for Primary Sjögren’s Syndrome |
| title_sort | biomarkers for primary sjogren s syndrome |
| topic | Biomarker Fms-like tyrosine kinase 3 ligand Myxovirus-resistance protein A Non-coding RNAs Saliva Sjögren syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S1672022915001059 |
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