A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway

A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line via the PI3K/AKT-TWIST1-Glycolysis Pathway

Non-small cell lung cancer (NSCLC) is a worldwide disease with a high morbidity and mortality rate, which is most derived from its metastasis. Some studies show that the epithelial–mesenchymal transition (EMT) process promotes lung cancer cell migration and invasion, leading to NSCLC metastasis. Tot...

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Bibliographic Details
Main Authors: Hui-Juan Cao, Wei Zhou, Xiao-Le Xian, Shu-Jun Sun, Pei-Jie Ding, Chun-Yu Tian, Fu-Ling Tian, Chun-Hua Jiang, Ting-Ting Fu, Shu Zhao, Jian-Ye Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Pharmacology
Subjects:
epithelial–mesenchymal transition
reconstructed TFAE
stable isotope dimethyl-labeled proteomics
Twist1
PI3K/Akt signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.821485/full

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