Could secondary prevention of coronary heart disease be more effective?

Beta-adrenoblockers (BAB) in secondary prevention of coronary heart disease (CHD) are not always effective, due to non-achieved target heart rate (HR). The reasons for that could include medication intolerance, baseline bradycardia (HR<55 bpm), II-III Stage atrio-ventricular blocks, and acute...

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Bibliographic Details
Main Author: V. I. Makolkin
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2010-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2022
Description
Summary:Beta-adrenoblockers (BAB) in secondary prevention of coronary heart disease (CHD) are not always effective, due to non-achieved target heart rate (HR). The reasons for that could include medication intolerance, baseline bradycardia (HR<55 bpm), II-III Stage atrio-ventricular blocks, and acute episodes of generalized weakness when HR is reduced. In these situations, BAB could be effectively combined with ivabradine (10-15 mg/d). This combination provides an opportunity to achieve target HR levels (60-55 bpm).
ISSN:1728-8800
2619-0125