Polymorphisms in Plasmodium falciparum dihydropteroate synthetase and dihydrofolate reductase genes in Nigerian children with uncomplicated malaria using high-resolution melting technique

Polymorphisms in Plasmodium falciparum dihydropteroate synthetase and dihydrofolate reductase genes in Nigerian children with uncomplicated malaria using high-resolution melting technique

Abstract In 2005, the Nigerian Federal Ministry of Health revised the treatment policy for uncomplicated malaria with the introduction of artemisinin-based combination therapies (ACTs). This policy change discouraged the use of Sulphadoxine-pyrimethamine (SP) as the second-line treatment of uncompli...

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Bibliographic Details
Main Authors:	Adeyemi T. Kayode, Fehintola V. Ajogbasile, Kazeem Akano, Jessica N. Uwanibe, Paul E. Oluniyi, Philomena J. Eromon, Onikepe A. Folarin, Akintunde Sowunmi, Dyann F. Wirth, Christian T. Happi
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-01-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-020-80017-6

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