The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly

Danny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affec...

Full description

Bibliographic Details
Main Authors: Danny Ulahannan, Adrian Wagg
Format: Article
Language:English
Published: Dove Medical Press 2009-04-01
Series:Clinical Interventions in Aging
Subjects:
Online Access:https://www.dovepress.com/the-safety-and-efficacy-of-tolterodine-extended-release-in-the-treatme-peer-reviewed-article-CIA
_version_ 1818571121419616256
author Danny Ulahannan
Adrian Wagg
author_facet Danny Ulahannan
Adrian Wagg
author_sort Danny Ulahannan
collection DOAJ
description Danny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies.Keywords: overactive bladder, tolterodine, urgency incontinence
first_indexed 2024-12-14T13:51:23Z
format Article
id doaj.art-7ecdbb11e6b34920961bfaa4c66f2845
institution Directory Open Access Journal
issn 1178-1998
language English
last_indexed 2024-12-14T13:51:23Z
publishDate 2009-04-01
publisher Dove Medical Press
record_format Article
series Clinical Interventions in Aging
spelling doaj.art-7ecdbb11e6b34920961bfaa4c66f28452022-12-21T22:59:04ZengDove Medical PressClinical Interventions in Aging1178-19982009-04-01Volume 41911963065The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderlyDanny UlahannanAdrian WaggDanny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies.Keywords: overactive bladder, tolterodine, urgency incontinencehttps://www.dovepress.com/the-safety-and-efficacy-of-tolterodine-extended-release-in-the-treatme-peer-reviewed-article-CIAoveractive bladdertolterodineurgency incontinence
spellingShingle Danny Ulahannan
Adrian Wagg
The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
Clinical Interventions in Aging
overactive bladder
tolterodine
urgency incontinence
title The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_full The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_fullStr The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_full_unstemmed The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_short The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
title_sort safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
topic overactive bladder
tolterodine
urgency incontinence
url https://www.dovepress.com/the-safety-and-efficacy-of-tolterodine-extended-release-in-the-treatme-peer-reviewed-article-CIA
work_keys_str_mv AT dannyulahannan thesafetyandefficacyoftolterodineextendedreleaseinthetreatmentofoveractivebladderintheelderly
AT adrianwagg thesafetyandefficacyoftolterodineextendedreleaseinthetreatmentofoveractivebladderintheelderly
AT dannyulahannan safetyandefficacyoftolterodineextendedreleaseinthetreatmentofoveractivebladderintheelderly
AT adrianwagg safetyandefficacyoftolterodineextendedreleaseinthetreatmentofoveractivebladderintheelderly