The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
Danny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affec...
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Format: | Article |
Language: | English |
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Dove Medical Press
2009-04-01
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Series: | Clinical Interventions in Aging |
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Online Access: | https://www.dovepress.com/the-safety-and-efficacy-of-tolterodine-extended-release-in-the-treatme-peer-reviewed-article-CIA |
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author | Danny Ulahannan Adrian Wagg |
author_facet | Danny Ulahannan Adrian Wagg |
author_sort | Danny Ulahannan |
collection | DOAJ |
description | Danny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies.Keywords: overactive bladder, tolterodine, urgency incontinence |
first_indexed | 2024-12-14T13:51:23Z |
format | Article |
id | doaj.art-7ecdbb11e6b34920961bfaa4c66f2845 |
institution | Directory Open Access Journal |
issn | 1178-1998 |
language | English |
last_indexed | 2024-12-14T13:51:23Z |
publishDate | 2009-04-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Clinical Interventions in Aging |
spelling | doaj.art-7ecdbb11e6b34920961bfaa4c66f28452022-12-21T22:59:04ZengDove Medical PressClinical Interventions in Aging1178-19982009-04-01Volume 41911963065The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderlyDanny UlahannanAdrian WaggDanny Ulahannan, Adrian WaggDepartment of Geriatric Medicine, University College Hospital, London, UKAbstract: After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies.Keywords: overactive bladder, tolterodine, urgency incontinencehttps://www.dovepress.com/the-safety-and-efficacy-of-tolterodine-extended-release-in-the-treatme-peer-reviewed-article-CIAoveractive bladdertolterodineurgency incontinence |
spellingShingle | Danny Ulahannan Adrian Wagg The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly Clinical Interventions in Aging overactive bladder tolterodine urgency incontinence |
title | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_full | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_fullStr | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_full_unstemmed | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_short | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_sort | safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
topic | overactive bladder tolterodine urgency incontinence |
url | https://www.dovepress.com/the-safety-and-efficacy-of-tolterodine-extended-release-in-the-treatme-peer-reviewed-article-CIA |
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