Synthesis, Characterization and In Vitro Evaluation of Chitosan Nanoparticles Physically Admixed with Lactose Microspheres for Pulmonary Delivery of Montelukast

Synthesis, Characterization and In Vitro Evaluation of Chitosan Nanoparticles Physically Admixed with Lactose Microspheres for Pulmonary Delivery of Montelukast

This study aimed to synthesise montelukast-loaded polymeric nanoparticles via the ionic gelation method using chitosan as a natural polymer and tripolyphosphate as a crosslinking agent. Tween 80, hyaluronic acid and leucine were added to modify the physicochemical properties of nanoparticles, reduce...

Full description

Bibliographic Details
Main Authors: Faqir Ullah, Kifayat Ullah Shah, Shefaat Ullah Shah, Asif Nawaz, Touseef Nawaz, Kamran Ahmad Khan, Raed F. Alserihi, Hossam H. Tayeb, Shams Tabrez, Mulham Alfatama
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Polymers
Subjects:
montelukast
chitosan
lactose
nanoparticles
microspheres
inhalation drug delivery
Online Access:https://www.mdpi.com/2073-4360/14/17/3564

Internet

https://www.mdpi.com/2073-4360/14/17/3564

Similar Items