Inhibition of VMAT2 by β2-adrenergic agonists, antagonists, and the atypical antipsychotic ziprasidone
Several existing β2-adrenergic agonists and antagonists, as well as the atypical antipsychotic ziprasidone, are identified as high affinity VMAT2 inhibitors, which could have implications for drug repurposing and drug derivatization campaigns.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04121-1 |