Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies
Mild cognitive impairment (MCI) is a multifactorial and complex central neurodegenerative disease. Acupuncture appears to be an effective method for cognitive function improvement in MCI patients. Neural plasticity remaining in the MCI brain implies that acupuncture-associated benefits may not be li...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1007436/full |
| _version_ | 1797924507148615680 |
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| author | Zihan Yin Zihan Yin Jun Zhou Manze Xia Manze Xia Zhenghong Chen Zhenghong Chen Yaqin Li Xinyue Zhang Xinyue Zhang Xiang Li Xiang Li Hang Yan Lu Wang Mingsheng Sun Mingsheng Sun Ling Zhao Ling Zhao Fanrong Liang Fanrong Liang Ziwen Wang Ziwen Wang |
| author_facet | Zihan Yin Zihan Yin Jun Zhou Manze Xia Manze Xia Zhenghong Chen Zhenghong Chen Yaqin Li Xinyue Zhang Xinyue Zhang Xiang Li Xiang Li Hang Yan Lu Wang Mingsheng Sun Mingsheng Sun Ling Zhao Ling Zhao Fanrong Liang Fanrong Liang Ziwen Wang Ziwen Wang |
| author_sort | Zihan Yin |
| collection | DOAJ |
| description | Mild cognitive impairment (MCI) is a multifactorial and complex central neurodegenerative disease. Acupuncture appears to be an effective method for cognitive function improvement in MCI patients. Neural plasticity remaining in the MCI brain implies that acupuncture-associated benefits may not be limited to the cognitive function. Instead, neurological alternations in the brain play a vital role in corresponding to the cognitive improvement. However, previous studies have mainly focused on the effects of cognitive function, leaving neurological findings relatively unclear. This systematic review summarized existing studies that used various brain imaging techniques to explore the neurological effect regarding acupuncture use for MCI treatment. Potential neuroimaging trials were searched, collected, and identified independently by two researchers. Four Chinese databases, four English databases, and additional sources were searched to identify studies reporting the use of acupuncture for MCI from the inception of databases until 1 June 2022. Methodological quality was appraised using the Cochrane risk-of-bias tool. In addition, general, methodological, and brain neuroimaging information was extracted and summarized to investigate the potential neural mechanisms by which acupuncture affects patients with MCI. In total, 22 studies involving 647 participants were included. The methodological quality of the included studies was moderate to high. The methods used included functional magnetic resonance imaging, diffusion tensor imaging, functional near-infrared spectroscopy, and magnetic resonance spectroscopy. Acupuncture-induced brain alterations observed in those patients with MCI tended to be observable in the cingulate cortex, prefrontal cortex, and hippocampus. The effect of acupuncture on MCI may play a role in regulating the default mode network, central executive network, and salience network. Based on these studies, researchers could extend the recent research focus from the cognitive domain to the neurological level. Future researches should develop additional relevant, well-designed, high-quality, and multimodal neuroimaging researches to detect the effects of acupuncture on the brains of MCI patients. |
| first_indexed | 2024-04-10T15:02:07Z |
| format | Article |
| id | doaj.art-7ed33985281f43f28eed74a918ad2b6e |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-04-10T15:02:07Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-7ed33985281f43f28eed74a918ad2b6e2023-02-15T09:56:44ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652023-02-011510.3389/fnagi.2023.10074361007436Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studiesZihan Yin0Zihan Yin1Jun Zhou2Manze Xia3Manze Xia4Zhenghong Chen5Zhenghong Chen6Yaqin Li7Xinyue Zhang8Xinyue Zhang9Xiang Li10Xiang Li11Hang Yan12Lu Wang13Mingsheng Sun14Mingsheng Sun15Ling Zhao16Ling Zhao17Fanrong Liang18Fanrong Liang19Ziwen Wang20Ziwen Wang21School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Basic Medicine, Zhejiang University of Traditional Chinese Medicine, Hangzhou, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaSchool of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaAcupuncture Clinical Research Center of Sichuan Province, Chengdu, ChinaMild cognitive impairment (MCI) is a multifactorial and complex central neurodegenerative disease. Acupuncture appears to be an effective method for cognitive function improvement in MCI patients. Neural plasticity remaining in the MCI brain implies that acupuncture-associated benefits may not be limited to the cognitive function. Instead, neurological alternations in the brain play a vital role in corresponding to the cognitive improvement. However, previous studies have mainly focused on the effects of cognitive function, leaving neurological findings relatively unclear. This systematic review summarized existing studies that used various brain imaging techniques to explore the neurological effect regarding acupuncture use for MCI treatment. Potential neuroimaging trials were searched, collected, and identified independently by two researchers. Four Chinese databases, four English databases, and additional sources were searched to identify studies reporting the use of acupuncture for MCI from the inception of databases until 1 June 2022. Methodological quality was appraised using the Cochrane risk-of-bias tool. In addition, general, methodological, and brain neuroimaging information was extracted and summarized to investigate the potential neural mechanisms by which acupuncture affects patients with MCI. In total, 22 studies involving 647 participants were included. The methodological quality of the included studies was moderate to high. The methods used included functional magnetic resonance imaging, diffusion tensor imaging, functional near-infrared spectroscopy, and magnetic resonance spectroscopy. Acupuncture-induced brain alterations observed in those patients with MCI tended to be observable in the cingulate cortex, prefrontal cortex, and hippocampus. The effect of acupuncture on MCI may play a role in regulating the default mode network, central executive network, and salience network. Based on these studies, researchers could extend the recent research focus from the cognitive domain to the neurological level. Future researches should develop additional relevant, well-designed, high-quality, and multimodal neuroimaging researches to detect the effects of acupuncture on the brains of MCI patients.https://www.frontiersin.org/articles/10.3389/fnagi.2023.1007436/fullacupuncturemild cognitive impairmentsystematic reviewneuroimagingmechanism |
| spellingShingle | Zihan Yin Zihan Yin Jun Zhou Manze Xia Manze Xia Zhenghong Chen Zhenghong Chen Yaqin Li Xinyue Zhang Xinyue Zhang Xiang Li Xiang Li Hang Yan Lu Wang Mingsheng Sun Mingsheng Sun Ling Zhao Ling Zhao Fanrong Liang Fanrong Liang Ziwen Wang Ziwen Wang Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies Frontiers in Aging Neuroscience acupuncture mild cognitive impairment systematic review neuroimaging mechanism |
| title | Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies |
| title_full | Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies |
| title_fullStr | Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies |
| title_full_unstemmed | Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies |
| title_short | Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies |
| title_sort | acupuncture on mild cognitive impairment a systematic review of neuroimaging studies |
| topic | acupuncture mild cognitive impairment systematic review neuroimaging mechanism |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2023.1007436/full |
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