Activation of Complement Pathways in Kidney Tissue May Mediate Tubulointerstitial Injury in Diabetic Nephropathy

Activation of Complement Pathways in Kidney Tissue May Mediate Tubulointerstitial Injury in Diabetic Nephropathy

IntroductionKey genes involved in tubulointerstitial injury may influence the development and progression of diabetic nephropathy (DN). We investigated whether complement-related genes are linked to the mechanism underlying tubulointerstitial injury in DN.MethodsWe analyzed the microarray data of 17...

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Bibliographic Details
Main Authors: Shimin Jiang, Yuanyuan Jiao, Guming Zou, Hongmei Gao, Li Zhuo, Wenge Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Medicine
Subjects:
diabetic nephropathy
tubulointerstitial injury
complement system
prognosis
WGCNA
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.845679/full

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