Research progress on the role of Klotho in heart failure
Klotho is an anti-aging protein and can be divided into three types: full-length transmembrane Klotho, soluble Klotho and secreted Klotho. Many studies have shown that Klotho is closely related to oxidative stress, inflammatory response, myocardial hypertrophy, fibrosis, autophagy, and mitochondrial...
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| Médium: | Článek |
| Jazyk: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2023-06-01
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| Edice: | Jichu yixue yu linchuang |
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| On-line přístup: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-6-998.pdf |
| Shrnutí: | Klotho is an anti-aging protein and can be divided into three types: full-length transmembrane Klotho, soluble Klotho and secreted Klotho. Many studies have shown that Klotho is closely related to oxidative stress, inflammatory response, myocardial hypertrophy, fibrosis, autophagy, and mitochondrial dysfunction. It is also involved in the occurrence and development of heart failure. It is expected to provide a new target and direction for the treatment of heart failure. |
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| ISSN: | 1001-6325 |