Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK)
We aim to assess the feasibility of topography-guided laser in situ keratomileusis (TOPOLINK) for correcting pre-existing and surgical-induced astigmatism. A retrospective, single center cohort study was conducted. Patients with pre-existing irregular myopic astigmatism were recruited into the prima...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-11-01
|
| Series: | Healthcare |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9032/8/4/477 |
| _version_ | 1797548195108093952 |
|---|---|
| author | Pei-Lun Wu Chia-Yi Lee Han-Chih Cheng Hung-Yu Lin Li-Ju Lai Wei-Chi Wu Hung-Chi Chen |
| author_facet | Pei-Lun Wu Chia-Yi Lee Han-Chih Cheng Hung-Yu Lin Li-Ju Lai Wei-Chi Wu Hung-Chi Chen |
| author_sort | Pei-Lun Wu |
| collection | DOAJ |
| description | We aim to assess the feasibility of topography-guided laser in situ keratomileusis (TOPOLINK) for correcting pre-existing and surgical-induced astigmatism. A retrospective, single center cohort study was conducted. Patients with pre-existing irregular myopic astigmatism were recruited into the primary group and those with irregular myopic astigmatism following laser in situ keratomileusis (LASIK) were recruited into the enhancement group. The changes in uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), maximum astigmatism, spherical equivalent (SE) and patient satisfaction were recorded. The Chi-square test, Mann–Whitney U test and Generalized Linear Mixed Model were utilized for the analysis in the current study. A total of 18 eyes were studied in the primary group and 14 eyes were examined in the enhancement group. One year postoperatively, the UCVA, BCVA, maximum astigmatism and SE improved significantly in both the primary and the enhancement groups (all <i>p</i> < 0.05). The UCVA (<i>p</i> = 0.046) and SE (<i>p</i> = 0.003) were worse in the primary group preoperatively but became similar in both groups postoperatively, while the BCVA and maximum astigmatism remained identical between groups throughout the study period (all <i>p</i> < 0.05). In addition, the rate of high and moderate satisfaction reached 90.0% in the primary and the enhancement groups, without significant differences (<i>p</i> = 0.871). In conclusion, the TOPOLINK showed high predictability and will contribute to similar outcomes between primary and postoperative irregular myopic astigmatism concerning visual acuity, refractive status and subject satisfaction. |
| first_indexed | 2024-03-10T14:55:56Z |
| format | Article |
| id | doaj.art-7edcc17a8f90414c9b1052f2ddcb2f59 |
| institution | Directory Open Access Journal |
| issn | 2227-9032 |
| language | English |
| last_indexed | 2024-03-10T14:55:56Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Healthcare |
| spelling | doaj.art-7edcc17a8f90414c9b1052f2ddcb2f592023-11-20T20:38:15ZengMDPI AGHealthcare2227-90322020-11-018447710.3390/healthcare8040477Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK)Pei-Lun Wu0Chia-Yi Lee1Han-Chih Cheng2Hung-Yu Lin3Li-Ju Lai4Wei-Chi Wu5Hung-Chi Chen6Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61301, TaiwanDepartment of Ophthalmology, Show Chwan Memorial Hospital, Changhua 50093, TaiwanDepartment of Ophthalmology, Buddhist Tzu Chi Hospital, Taipei 23142, TaiwanDepartment of Ophthalmology, Show Chwan Memorial Hospital, Changhua 50093, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 61301, TaiwanDepartment of Medicine, Chang Gung University College of Medicine, Taoyuan 33302, TaiwanDepartment of Medicine, Chang Gung University College of Medicine, Taoyuan 33302, TaiwanWe aim to assess the feasibility of topography-guided laser in situ keratomileusis (TOPOLINK) for correcting pre-existing and surgical-induced astigmatism. A retrospective, single center cohort study was conducted. Patients with pre-existing irregular myopic astigmatism were recruited into the primary group and those with irregular myopic astigmatism following laser in situ keratomileusis (LASIK) were recruited into the enhancement group. The changes in uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), maximum astigmatism, spherical equivalent (SE) and patient satisfaction were recorded. The Chi-square test, Mann–Whitney U test and Generalized Linear Mixed Model were utilized for the analysis in the current study. A total of 18 eyes were studied in the primary group and 14 eyes were examined in the enhancement group. One year postoperatively, the UCVA, BCVA, maximum astigmatism and SE improved significantly in both the primary and the enhancement groups (all <i>p</i> < 0.05). The UCVA (<i>p</i> = 0.046) and SE (<i>p</i> = 0.003) were worse in the primary group preoperatively but became similar in both groups postoperatively, while the BCVA and maximum astigmatism remained identical between groups throughout the study period (all <i>p</i> < 0.05). In addition, the rate of high and moderate satisfaction reached 90.0% in the primary and the enhancement groups, without significant differences (<i>p</i> = 0.871). In conclusion, the TOPOLINK showed high predictability and will contribute to similar outcomes between primary and postoperative irregular myopic astigmatism concerning visual acuity, refractive status and subject satisfaction.https://www.mdpi.com/2227-9032/8/4/477refractive errorastigmatismtopographylaser in situ keratomileusis |
| spellingShingle | Pei-Lun Wu Chia-Yi Lee Han-Chih Cheng Hung-Yu Lin Li-Ju Lai Wei-Chi Wu Hung-Chi Chen Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK) Healthcare refractive error astigmatism topography laser in situ keratomileusis |
| title | Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK) |
| title_full | Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK) |
| title_fullStr | Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK) |
| title_full_unstemmed | Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK) |
| title_short | Correction of Myopic Astigmatism with Topography-Guided Laser In Situ Keratomileusis (TOPOLINK) |
| title_sort | correction of myopic astigmatism with topography guided laser in situ keratomileusis topolink |
| topic | refractive error astigmatism topography laser in situ keratomileusis |
| url | https://www.mdpi.com/2227-9032/8/4/477 |
| work_keys_str_mv | AT peilunwu correctionofmyopicastigmatismwithtopographyguidedlaserinsitukeratomileusistopolink AT chiayilee correctionofmyopicastigmatismwithtopographyguidedlaserinsitukeratomileusistopolink AT hanchihcheng correctionofmyopicastigmatismwithtopographyguidedlaserinsitukeratomileusistopolink AT hungyulin correctionofmyopicastigmatismwithtopographyguidedlaserinsitukeratomileusistopolink AT lijulai correctionofmyopicastigmatismwithtopographyguidedlaserinsitukeratomileusistopolink AT weichiwu correctionofmyopicastigmatismwithtopographyguidedlaserinsitukeratomileusistopolink AT hungchichen correctionofmyopicastigmatismwithtopographyguidedlaserinsitukeratomileusistopolink |