Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm Infants
The present study aimed to compare the bilevel volume guarantee (VG) and pressure-regulated volume control (PRVC) modes of the GE<sup>®</sup> Carescape R860 model ventilator and test the safety and feasibility of these two modes in preterm neonates. Infants who were less than 30 weeks of...
| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Makale |
| Dil: | English |
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MDPI AG
2023-09-01
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| Seri Bilgileri: | Children |
| Konular: | |
| Online Erişim: | https://www.mdpi.com/2227-9067/10/10/1603 |
| _version_ | 1827721376625065984 |
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| author | Şehribanu Işık Fuat Emre Canpolat Gülsüm Kadıoğlu Şimşek Ömer Ertekin Hayriye Gözde Kanmaz Kutman |
| author_facet | Şehribanu Işık Fuat Emre Canpolat Gülsüm Kadıoğlu Şimşek Ömer Ertekin Hayriye Gözde Kanmaz Kutman |
| author_sort | Şehribanu Işık |
| collection | DOAJ |
| description | The present study aimed to compare the bilevel volume guarantee (VG) and pressure-regulated volume control (PRVC) modes of the GE<sup>®</sup> Carescape R860 model ventilator and test the safety and feasibility of these two modes in preterm neonates. Infants who were less than 30 weeks of gestational age were included. After randomization, initial ventilator settings were adjusted for each patient. After the first 2 h of ventilation, the patients were switched to the other ventilator mode for 2 h. The ventilator parameters, vital signs, and blood gas values were evaluated. The study included a total of 28 patients, 14 in the PRVC group and 14 in the bilevel VG group. The mean birth weight was 876 g (range: 530–1170) and the mean gestational age was 26.4 weeks (range: 24–29). The patients’ peak inspiratory pressure (PIP<sub>2</sub> and PIP<sub>3</sub>) was lower after ventilation in bilevel VG mode than in PRVC mode (13 vs. 14 cmH<sub>2</sub>O, respectively; paired samples <i>t</i>-test, <i>p</i> = 0.008). After 2 h of bilevel VG ventilation, the mean heart rate decreased from 149/min to 140/min (<i>p</i> = 0.001) and the oxygen saturation increased from 91% to 94% (<i>p</i> = 0.01). Both the PRVC and bilevel VG modes of GE ventilators can be used safely in preterm infants, and bilevel VG mode was associated with more favorable early clinical findings. Studies including more patients and comparing with other modes will clarify and provide further evidence on this subject. |
| first_indexed | 2024-03-10T21:20:43Z |
| format | Article |
| id | doaj.art-7edd21039b3346cbb665badb5bead62b |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-10T21:20:43Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-7edd21039b3346cbb665badb5bead62b2023-11-19T16:04:26ZengMDPI AGChildren2227-90672023-09-011010160310.3390/children10101603Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm InfantsŞehribanu Işık0Fuat Emre Canpolat1Gülsüm Kadıoğlu Şimşek2Ömer Ertekin3Hayriye Gözde Kanmaz Kutman4Department of Neonatology, University of Health Sciences, Ankara City Hospital MH5, Çankaya, Ankara 06800, TurkeyDepartment of Neonatology, University of Health Sciences, Ankara City Hospital MH5, Çankaya, Ankara 06800, TurkeyDepartment of Neonatology, University of Health Sciences, Ankara City Hospital MH5, Çankaya, Ankara 06800, TurkeyDepartment of Neonatology, University of Health Sciences, Ankara City Hospital MH5, Çankaya, Ankara 06800, TurkeyDepartment of Neonatology, University of Health Sciences, Ankara City Hospital MH5, Çankaya, Ankara 06800, TurkeyThe present study aimed to compare the bilevel volume guarantee (VG) and pressure-regulated volume control (PRVC) modes of the GE<sup>®</sup> Carescape R860 model ventilator and test the safety and feasibility of these two modes in preterm neonates. Infants who were less than 30 weeks of gestational age were included. After randomization, initial ventilator settings were adjusted for each patient. After the first 2 h of ventilation, the patients were switched to the other ventilator mode for 2 h. The ventilator parameters, vital signs, and blood gas values were evaluated. The study included a total of 28 patients, 14 in the PRVC group and 14 in the bilevel VG group. The mean birth weight was 876 g (range: 530–1170) and the mean gestational age was 26.4 weeks (range: 24–29). The patients’ peak inspiratory pressure (PIP<sub>2</sub> and PIP<sub>3</sub>) was lower after ventilation in bilevel VG mode than in PRVC mode (13 vs. 14 cmH<sub>2</sub>O, respectively; paired samples <i>t</i>-test, <i>p</i> = 0.008). After 2 h of bilevel VG ventilation, the mean heart rate decreased from 149/min to 140/min (<i>p</i> = 0.001) and the oxygen saturation increased from 91% to 94% (<i>p</i> = 0.01). Both the PRVC and bilevel VG modes of GE ventilators can be used safely in preterm infants, and bilevel VG mode was associated with more favorable early clinical findings. Studies including more patients and comparing with other modes will clarify and provide further evidence on this subject.https://www.mdpi.com/2227-9067/10/10/1603bilevel volume guaranteepressure-regulated volume controlpretermmechanical ventilation |
| spellingShingle | Şehribanu Işık Fuat Emre Canpolat Gülsüm Kadıoğlu Şimşek Ömer Ertekin Hayriye Gözde Kanmaz Kutman Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm Infants Children bilevel volume guarantee pressure-regulated volume control preterm mechanical ventilation |
| title | Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm Infants |
| title_full | Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm Infants |
| title_fullStr | Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm Infants |
| title_full_unstemmed | Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm Infants |
| title_short | Comparison of Bilevel Volume Guarantee and Pressure-Regulated Volume Control Modes in Preterm Infants |
| title_sort | comparison of bilevel volume guarantee and pressure regulated volume control modes in preterm infants |
| topic | bilevel volume guarantee pressure-regulated volume control preterm mechanical ventilation |
| url | https://www.mdpi.com/2227-9067/10/10/1603 |
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