Cholesterol Metabolism in Antigen-Presenting Cells and HIV-1 Trans-Infection of CD4<sup>+</sup> T Cells

Antiretroviral therapy (ART) provides an effective method for managing HIV-1 infection and preventing the onset of AIDS; however, it is ineffective against the reservoir of latent HIV-1 that persists predominantly in resting CD4<sup>+</sup> T cells. Understanding the mechanisms that faci...

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Bibliographic Details
Main Authors: Daniel Okpaise, Nicolas Sluis-Cremer, Giovanna Rappocciolo, Charles R. Rinaldo
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/12/2347