The Effects of Endoplasmic Reticulum Stress via Intratracheal Instillation of Water-Soluble Acrylic Acid Polymer on the Lungs of Rats

The Effects of Endoplasmic Reticulum Stress via Intratracheal Instillation of Water-Soluble Acrylic Acid Polymer on the Lungs of Rats

Polyacrylic acid (PAA), an organic chemical, has been used as an intermediate in the manufacture of pharmaceuticals and cosmetics. It has been suggested recently that PAA has a high pulmonary inflammatory and fibrotic potential. Although endoplasmic reticulum stress is induced by various external an...

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Bibliographic Details
Main Authors: Toshiki Morimoto, Hiroto Izumi, Taisuke Tomonaga, Chinatsu Nishida, Naoki Kawai, Yasuyuki Higashi, Ke-Yong Wang, Ryohei Ono, Kazuki Sumiya, Kazuo Sakurai, Akihiro Moriyama, Jun-ichi Takeshita, Kei Yamasaki, Kazuhiro Yatera, Yasuo Morimoto
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
polyacrylic acid (PAA)
organic compounds
molecular weight
pulmonary toxicity
persistent inflammation
fibrosis
Online Access:https://www.mdpi.com/1422-0067/25/7/3573

Internet

https://www.mdpi.com/1422-0067/25/7/3573

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