Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large series
Purpose: To analyze the complications in patients managed with deep anterior lamellar keratoplasty (DALK) for diseases of the anterior corneal stroma. Methods: This is a retrospective analysis of all the patients who underwent DALK in a tertiary care center in South India from 2010 to 2020. A total...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Ophthalmology |
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| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3501;epage=3507;aulast=Kodavoor |
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| author | Shreesha Kumar Kodavoor Neha Rathi Ramamurthy Dandapani |
| author_facet | Shreesha Kumar Kodavoor Neha Rathi Ramamurthy Dandapani |
| author_sort | Shreesha Kumar Kodavoor |
| collection | DOAJ |
| description | Purpose: To analyze the complications in patients managed with deep anterior lamellar keratoplasty (DALK) for diseases of the anterior corneal stroma. Methods: This is a retrospective analysis of all the patients who underwent DALK in a tertiary care center in South India from 2010 to 2020. A total of 474 eyes in 373 patients were included in the study. Patients who underwent DALK for advanced keratoconus, keratoconus with Bowman's membrane scar, healed hydrops, macular corneal opacity, macular corneal dystrophy, granular corneal dystrophy, spheroidal degeneration, pellucid marginal degeneration, post–laser-assisted in situ keratomileusis ectasia, descematocele, post-collagen cross-linking aborted melt and dense scar, and post-radial keratotomy were included in the study. The patients were followed up for 17.2 +/- 9.2 months (1–9 years). Results: Complications noted in the surgery were intra-operatively Descemet's membrane perforation in 31 eyes (6.54%), post-operatively secondary glaucoma in 16 eyes (3.37%), cataract in seven eyes (1.47%), suture-related complications in five eyes (1.05%), graft rejection in three eyes (0.63%), traumatic dehiscence in two eyes (0.42%), filamentary keratitis in two eyes (0.42%), interface infiltrate in one eye (0.21%), and recurrence of disease in four eyes (7.14%) out of 57 eyes with corneal dystrophy. Conclusion: DALK as an alternative to penetrating keratoplasty for anterior corneal stromal diseases. It has become an automatic choice for diseases of the anterior cornea requiring keratoplasty. Complications can occur at any stage of surgery; however, if identified and managed early, they can result in optimal outcome. |
| first_indexed | 2024-04-12T13:01:44Z |
| format | Article |
| id | doaj.art-7ee35dde01c64e7a9084bddf3f3a8316 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-12T13:01:44Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-7ee35dde01c64e7a9084bddf3f3a83162022-12-22T03:32:09ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-0170103501350710.4103/ijo.IJO_655_22Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large seriesShreesha Kumar KodavoorNeha RathiRamamurthy DandapaniPurpose: To analyze the complications in patients managed with deep anterior lamellar keratoplasty (DALK) for diseases of the anterior corneal stroma. Methods: This is a retrospective analysis of all the patients who underwent DALK in a tertiary care center in South India from 2010 to 2020. A total of 474 eyes in 373 patients were included in the study. Patients who underwent DALK for advanced keratoconus, keratoconus with Bowman's membrane scar, healed hydrops, macular corneal opacity, macular corneal dystrophy, granular corneal dystrophy, spheroidal degeneration, pellucid marginal degeneration, post–laser-assisted in situ keratomileusis ectasia, descematocele, post-collagen cross-linking aborted melt and dense scar, and post-radial keratotomy were included in the study. The patients were followed up for 17.2 +/- 9.2 months (1–9 years). Results: Complications noted in the surgery were intra-operatively Descemet's membrane perforation in 31 eyes (6.54%), post-operatively secondary glaucoma in 16 eyes (3.37%), cataract in seven eyes (1.47%), suture-related complications in five eyes (1.05%), graft rejection in three eyes (0.63%), traumatic dehiscence in two eyes (0.42%), filamentary keratitis in two eyes (0.42%), interface infiltrate in one eye (0.21%), and recurrence of disease in four eyes (7.14%) out of 57 eyes with corneal dystrophy. Conclusion: DALK as an alternative to penetrating keratoplasty for anterior corneal stromal diseases. It has become an automatic choice for diseases of the anterior cornea requiring keratoplasty. Complications can occur at any stage of surgery; however, if identified and managed early, they can result in optimal outcome.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3501;epage=3507;aulast=Kodavoordeep anterior lamellar keratoplastydescemet's membrane perforationdouble anterior chambergraft rejectioninterface infectious keratitis |
| spellingShingle | Shreesha Kumar Kodavoor Neha Rathi Ramamurthy Dandapani Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large series Indian Journal of Ophthalmology deep anterior lamellar keratoplasty descemet's membrane perforation double anterior chamber graft rejection interface infectious keratitis |
| title | Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large series |
| title_full | Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large series |
| title_fullStr | Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large series |
| title_full_unstemmed | Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large series |
| title_short | Complications in deep anterior lamellar keratoplasty – A retrospective interventional analysis in a large series |
| title_sort | complications in deep anterior lamellar keratoplasty a retrospective interventional analysis in a large series |
| topic | deep anterior lamellar keratoplasty descemet's membrane perforation double anterior chamber graft rejection interface infectious keratitis |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=10;spage=3501;epage=3507;aulast=Kodavoor |
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