Tuberculosis elimination in the post Millennium Development Goals era

The Millennium Development Goal for tuberculosis (TB) is to stop the increase in incidence and halve the mortality of TB between 1990 and 2015. This goal has now been reached on a global scale, although not in the most affected region of Africa. The new target is TB elimination, defined as one case...

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Main Author: Christian Wejse
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971214017093
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author Christian Wejse
author_facet Christian Wejse
author_sort Christian Wejse
collection DOAJ
description The Millennium Development Goal for tuberculosis (TB) is to stop the increase in incidence and halve the mortality of TB between 1990 and 2015. This goal has now been reached on a global scale, although not in the most affected region of Africa. The new target is TB elimination, defined as one case of active TB per one million population per year, which is to be reached before 2050. This review will discuss the main tools in play, namely case-finding and new diagnostics, increased access and effectiveness of anti-TB therapy (directly observed therapy, short course (DOTS)), preventive therapy for latent infection, and vaccination. Each approach is discussed and a way forward in research and management is suggested.
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spelling doaj.art-7ee6649511c3413eae830782efbe8e752022-12-21T18:28:30ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112015-03-0132C15215510.1016/j.ijid.2014.11.020Tuberculosis elimination in the post Millennium Development Goals eraChristian Wejse0GloHAU, Center for Global Health, School of Public Health, Aarhus University, Bartholins Alle 2, 8000 Aarhus C, DenmarkThe Millennium Development Goal for tuberculosis (TB) is to stop the increase in incidence and halve the mortality of TB between 1990 and 2015. This goal has now been reached on a global scale, although not in the most affected region of Africa. The new target is TB elimination, defined as one case of active TB per one million population per year, which is to be reached before 2050. This review will discuss the main tools in play, namely case-finding and new diagnostics, increased access and effectiveness of anti-TB therapy (directly observed therapy, short course (DOTS)), preventive therapy for latent infection, and vaccination. Each approach is discussed and a way forward in research and management is suggested.http://www.sciencedirect.com/science/article/pii/S1201971214017093TuberculosisEliminationCase-findingPreventive therapy
spellingShingle Christian Wejse
Tuberculosis elimination in the post Millennium Development Goals era
International Journal of Infectious Diseases
Tuberculosis
Elimination
Case-finding
Preventive therapy
title Tuberculosis elimination in the post Millennium Development Goals era
title_full Tuberculosis elimination in the post Millennium Development Goals era
title_fullStr Tuberculosis elimination in the post Millennium Development Goals era
title_full_unstemmed Tuberculosis elimination in the post Millennium Development Goals era
title_short Tuberculosis elimination in the post Millennium Development Goals era
title_sort tuberculosis elimination in the post millennium development goals era
topic Tuberculosis
Elimination
Case-finding
Preventive therapy
url http://www.sciencedirect.com/science/article/pii/S1201971214017093
work_keys_str_mv AT christianwejse tuberculosiseliminationinthepostmillenniumdevelopmentgoalsera