Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand
Rotavirus A is a highly contagious virus that causes acute gastroenteritis in humans and a wide variety of animals. In this review, we summarized the information on rotavirus described in the studies in the last decade (2008 to 2021) in Thailand, including the prevalence, seasonality, genetic divers...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Tropical Medicine and Infectious Disease |
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| Online Access: | https://www.mdpi.com/2414-6366/8/7/347 |
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| author | Nutthawadee Jampanil Kattareeya Kumthip Niwat Maneekarn Pattara Khamrin |
| author_facet | Nutthawadee Jampanil Kattareeya Kumthip Niwat Maneekarn Pattara Khamrin |
| author_sort | Nutthawadee Jampanil |
| collection | DOAJ |
| description | Rotavirus A is a highly contagious virus that causes acute gastroenteritis in humans and a wide variety of animals. In this review, we summarized the information on rotavirus described in the studies in the last decade (2008 to 2021) in Thailand, including the prevalence, seasonality, genetic diversity, and interspecies transmission. The overall prevalence of rotavirus infection in humans ranged from 15–33%. Rotavirus infection was detected throughout the year and most frequently in the dry and cold months, typically in March. The diversity of rotavirus genotypes varied year to year and from region to region. From 2008 to 2016, rotavirus G1P[8] was detected as the most predominant genotype in Thailand. After 2016, G1P[8] decreased significantly and other genotypes including G3P[8], G8P[8], and G9P[8] were increasingly detected from 2016 to 2020. Several uncommon rotavirus strains such as G1P[6], G4P[6], and G3P[10] have also been occasionally detected. In addition, most studies on rotavirus A infection in animals in Thailand from 2011 to 2021 reported the detection of rotavirus A in piglets and canine species. It was reported that rotavirus could cross the host species barrier between humans and animals through interspecies transmission and genetic reassortment mechanisms. The surveillance of rotavirus infection is crucial to identify the trend of rotavirus infection and the emergence of novel rotavirus genotypes in this country. The data provide information on rotavirus infection and the diversity of rotavirus genotypes circulating in the pre-vaccination period, and the data will be useful for the evaluation of the effectiveness of rotavirus vaccine implementation in Thailand. |
| first_indexed | 2024-03-11T00:35:18Z |
| format | Article |
| id | doaj.art-7ef4ddfce3004a92a0ba68ebcd2ff5e4 |
| institution | Directory Open Access Journal |
| issn | 2414-6366 |
| language | English |
| last_indexed | 2024-03-11T00:35:18Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Tropical Medicine and Infectious Disease |
| spelling | doaj.art-7ef4ddfce3004a92a0ba68ebcd2ff5e42023-11-18T21:38:56ZengMDPI AGTropical Medicine and Infectious Disease2414-63662023-06-018734710.3390/tropicalmed8070347Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in ThailandNutthawadee Jampanil0Kattareeya Kumthip1Niwat Maneekarn2Pattara Khamrin3Department of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, ThailandRotavirus A is a highly contagious virus that causes acute gastroenteritis in humans and a wide variety of animals. In this review, we summarized the information on rotavirus described in the studies in the last decade (2008 to 2021) in Thailand, including the prevalence, seasonality, genetic diversity, and interspecies transmission. The overall prevalence of rotavirus infection in humans ranged from 15–33%. Rotavirus infection was detected throughout the year and most frequently in the dry and cold months, typically in March. The diversity of rotavirus genotypes varied year to year and from region to region. From 2008 to 2016, rotavirus G1P[8] was detected as the most predominant genotype in Thailand. After 2016, G1P[8] decreased significantly and other genotypes including G3P[8], G8P[8], and G9P[8] were increasingly detected from 2016 to 2020. Several uncommon rotavirus strains such as G1P[6], G4P[6], and G3P[10] have also been occasionally detected. In addition, most studies on rotavirus A infection in animals in Thailand from 2011 to 2021 reported the detection of rotavirus A in piglets and canine species. It was reported that rotavirus could cross the host species barrier between humans and animals through interspecies transmission and genetic reassortment mechanisms. The surveillance of rotavirus infection is crucial to identify the trend of rotavirus infection and the emergence of novel rotavirus genotypes in this country. The data provide information on rotavirus infection and the diversity of rotavirus genotypes circulating in the pre-vaccination period, and the data will be useful for the evaluation of the effectiveness of rotavirus vaccine implementation in Thailand.https://www.mdpi.com/2414-6366/8/7/347rotavirusdiarrheachildrenThailand |
| spellingShingle | Nutthawadee Jampanil Kattareeya Kumthip Niwat Maneekarn Pattara Khamrin Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand Tropical Medicine and Infectious Disease rotavirus diarrhea children Thailand |
| title | Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand |
| title_full | Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand |
| title_fullStr | Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand |
| title_full_unstemmed | Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand |
| title_short | Genetic Diversity of Rotaviruses Circulating in Pediatric Patients and Domestic Animals in Thailand |
| title_sort | genetic diversity of rotaviruses circulating in pediatric patients and domestic animals in thailand |
| topic | rotavirus diarrhea children Thailand |
| url | https://www.mdpi.com/2414-6366/8/7/347 |
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