Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma
This article discusses current approaches to first-line chemotherapy for non-resectable head and neck squamous cell carcinoma and describes factors affecting the choice of treatment regimen according to the results of randomized clinical trials. We provide a rationale for creating a long-term strate...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2022-04-01
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| Series: | Опухоли головы и шеи |
| Subjects: | |
| Online Access: | https://ogsh.abvpress.ru/jour/article/view/735 |
| _version_ | 1797876157788454912 |
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| author | L. V. Bolotina T. V. Ustinova T. I. Dеshkina P. V. Golubev N. N. Lyubavina A. A. Fedenko A. D. Kaprin |
| author_facet | L. V. Bolotina T. V. Ustinova T. I. Dеshkina P. V. Golubev N. N. Lyubavina A. A. Fedenko A. D. Kaprin |
| author_sort | L. V. Bolotina |
| collection | DOAJ |
| description | This article discusses current approaches to first-line chemotherapy for non-resectable head and neck squamous cell carcinoma and describes factors affecting the choice of treatment regimen according to the results of randomized clinical trials. We provide a rationale for creating a long-term strategy of chemotherapy in different clinical situations. We also report two cases of concomitant administration of cetuximab and platinum-based therapy as an example of high efficacy of monoclonal antibodies. |
| first_indexed | 2024-04-10T01:58:44Z |
| format | Article |
| id | doaj.art-7ef5a787f1684a399160ab6d43dca91e |
| institution | Directory Open Access Journal |
| issn | 2222-1468 2411-4634 |
| language | Russian |
| last_indexed | 2024-04-10T01:58:44Z |
| publishDate | 2022-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли головы и шеи |
| spelling | doaj.art-7ef5a787f1684a399160ab6d43dca91e2023-03-13T08:43:22ZrusABV-pressОпухоли головы и шеи2222-14682411-46342022-04-01121355210.17650/2222-1468-2022-12-1-35-52479Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinomaL. V. Bolotina0T. V. Ustinova1T. I. Dеshkina2P. V. Golubev3N. N. Lyubavina4A. A. Fedenko5A. D. Kaprin6Московский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава РоссииМосковский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава РоссииМосковский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава РоссииМосковский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава РоссииМосковский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава РоссииМосковский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава РоссииМосковский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России; ФГАОУ ВО «Российский университет дружбы народов»This article discusses current approaches to first-line chemotherapy for non-resectable head and neck squamous cell carcinoma and describes factors affecting the choice of treatment regimen according to the results of randomized clinical trials. We provide a rationale for creating a long-term strategy of chemotherapy in different clinical situations. We also report two cases of concomitant administration of cetuximab and platinum-based therapy as an example of high efficacy of monoclonal antibodies.https://ogsh.abvpress.ru/jour/article/view/735опухоли головы и шеихимиотерапиямоноклональные антителацетуксимабиммунотерапия |
| spellingShingle | L. V. Bolotina T. V. Ustinova T. I. Dеshkina P. V. Golubev N. N. Lyubavina A. A. Fedenko A. D. Kaprin Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma Опухоли головы и шеи опухоли головы и шеи химиотерапия моноклональные антитела цетуксимаб иммунотерапия |
| title | Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma |
| title_full | Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma |
| title_fullStr | Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma |
| title_full_unstemmed | Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma |
| title_short | Rational sequence of monoclonal antibodies in the treatment of non-resectable head and neck squamous cell carcinoma |
| title_sort | rational sequence of monoclonal antibodies in the treatment of non resectable head and neck squamous cell carcinoma |
| topic | опухоли головы и шеи химиотерапия моноклональные антитела цетуксимаб иммунотерапия |
| url | https://ogsh.abvpress.ru/jour/article/view/735 |
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