Effect of rs2293347 Polymorphism in EGFR on the Clinical Efficacy of Gefitinib 
in Patients with Non-small Cell Lung Cancer

Effect of rs2293347 Polymorphism in EGFR on the Clinical Efficacy of Gefitinib 
in Patients with Non-small Cell Lung Cancer

Background and objective Genetic variations of the epidermal growth factor receptor (EGFR) may alter the protein function and therapeutic efficacy of EGFR inhibitors. The aim of this study is to investigate the association between single nucleotide polymorphism rs2293347 in EGFR and the clinical out...

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Bibliographic Details
Main Authors: Fei MA, Binghe XU, Dongxin LIN, Tong SUN, Yuankai SHI
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2011-08-01
Series:Chinese Journal of Lung Cancer
Subjects:
Lung neoplasms
Epidermal growth factor receptor (EGFR)
Gefitinib
Single nucleotide polymorphism
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2011.08.02

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