Extracorporeal Treatments for Abdominal Sepsis

In spite of considerable progress in the intensive treatment of abdominal sepsis, mortality from this disease remains very high. A systemic inflammatory response to infection is characterized by the blood flow release of endotoxin and inflammatory mediators, which cause circulatory disorders and mul...

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Bibliographic Details
Main Authors: E. S. Bazhina, A. V. Nikulin, S. E. Khoroshilov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2015-10-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1486
Description
Summary:In spite of considerable progress in the intensive treatment of abdominal sepsis, mortality from this disease remains very high. A systemic inflammatory response to infection is characterized by the blood flow release of endotoxin and inflammatory mediators, which cause circulatory disorders and multiple organ dysfunctions. High frequency Doppler ultrasound allows dynamic estimation of tissue perfusion during efferent treatment. Objective: to give an account of current approaches to extracorporeal treatment for abdominal sepsis in the light of urgent views on the pathogenesis of bacterial translocation and a systemic inflammatory response, as well as macrohemodynamic disorders and tissue perfusion failure.
ISSN:1813-9779
2411-7110