Development of a concentration‐controlled sequential nanoprecipitation for making lipid nanoparticles with high drug loading

Development of a concentration‐controlled sequential nanoprecipitation for making lipid nanoparticles with high drug loading

Abstract Lipid‐based nanostructures have garnered considerable interests over the last two decades, and have achieved tremendous clinical success including the first clinical approval of a liposome (Doxil) for cancer therapy in 1995 and the recent COVID‐19 mRNA lipid nanoparticle vaccines. Compared...

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Bibliographic Details
Main Authors: Letao Xu, Xing Wang, Guangze Yang, Zihan Zhao, Yilun Weng, Yang Li, Yun Liu, Chun‐Xia Zhao
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Aggregate
Subjects:
controlled release
drug delivery
drug loading
lipid nanoparticles
nanoprecipitation
Online Access:https://doi.org/10.1002/agt2.369

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