Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation

Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation

Abstract Background Cardiac fibroblast activation protein (FAP) has an emerging role in heart failure (HF). A paradoxical reduction in its levels in pathological conditions associated with acute processes has been observed. We aimed to identify FAP cardiac tissue expression and its relationship with...

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Bibliographic Details
Main Authors: Marta Delgado-Arija, Patricia Genovés, Lorena Pérez-Carrillo, Irene González-Torrent, Isaac Giménez-Escamilla, Luis Martínez-Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló-Lletí
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
Heart failure
FAP
Cardiac fibroblasts
Fibrosis
microRNAs
Acute heart failure
Online Access:https://doi.org/10.1186/s12967-024-04900-w

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