Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera)
Sacred lotus (Nelumbo nucifera) is a 2,000-year-old perennial rhizome aquatic crop that is primarily employed as a food and drug dual-use crop in East Asia. One of the key bioactive components of sacred lotus is benzylisoquinoline alkaloids (BIAs). Existing research has demonstrated that they have t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Maximum Academic Press
2023-02-01
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| Series: | Medicinal Plant Biology |
| Subjects: | |
| Online Access: | https://www.maxapress.com/article/doi/10.48130/MPB-2023-0020 |
| _version_ | 1827070493110304768 |
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| author | Zhuyin Chen Hedi Zhao Sha Chen |
| author_facet | Zhuyin Chen Hedi Zhao Sha Chen |
| author_sort | Zhuyin Chen |
| collection | DOAJ |
| description | Sacred lotus (Nelumbo nucifera) is a 2,000-year-old perennial rhizome aquatic crop that is primarily employed as a food and drug dual-use crop in East Asia. One of the key bioactive components of sacred lotus is benzylisoquinoline alkaloids (BIAs). Existing research has demonstrated that they have therapeutic and preventive benefits on obesity, diabetes, cancer, and cardiovascular disease. Despite their broad pharmacological relevance, the metabolism of BIA in sacred lotus has received little attention. We reviewed the biosynthetic process of the BIA in sacred lotus in this research. We concluded that a thorough functional characterization of BIAs biosynthesis enzymes provides a wide range of significant therapeutic applications for sacred lotus. |
| first_indexed | 2024-03-07T16:23:46Z |
| format | Article |
| id | doaj.art-7f00fcaa4669445ba970689dcb70cb6a |
| institution | Directory Open Access Journal |
| issn | 2835-6969 |
| language | English |
| last_indexed | 2025-03-20T00:23:23Z |
| publishDate | 2023-02-01 |
| publisher | Maximum Academic Press |
| record_format | Article |
| series | Medicinal Plant Biology |
| spelling | doaj.art-7f00fcaa4669445ba970689dcb70cb6a2024-10-10T08:49:35ZengMaximum Academic PressMedicinal Plant Biology2835-69692023-02-01211710.48130/MPB-2023-0020MPB-2023-0020Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera)Zhuyin Chen0Hedi Zhao1Sha Chen2Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No.16, Nanxiaojie, Dongzhimennei, Beijing 100700, ChinaKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No.16, Nanxiaojie, Dongzhimennei, Beijing 100700, ChinaKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, No.16, Nanxiaojie, Dongzhimennei, Beijing 100700, ChinaSacred lotus (Nelumbo nucifera) is a 2,000-year-old perennial rhizome aquatic crop that is primarily employed as a food and drug dual-use crop in East Asia. One of the key bioactive components of sacred lotus is benzylisoquinoline alkaloids (BIAs). Existing research has demonstrated that they have therapeutic and preventive benefits on obesity, diabetes, cancer, and cardiovascular disease. Despite their broad pharmacological relevance, the metabolism of BIA in sacred lotus has received little attention. We reviewed the biosynthetic process of the BIA in sacred lotus in this research. We concluded that a thorough functional characterization of BIAs biosynthesis enzymes provides a wide range of significant therapeutic applications for sacred lotus.https://www.maxapress.com/article/doi/10.48130/MPB-2023-0020benzylisoquinoline alkaloidsnelumbo nuciferasacred lotusbiosynthesis |
| spellingShingle | Zhuyin Chen Hedi Zhao Sha Chen Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera) Medicinal Plant Biology benzylisoquinoline alkaloids nelumbo nucifera sacred lotus biosynthesis |
| title | Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera) |
| title_full | Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera) |
| title_fullStr | Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera) |
| title_full_unstemmed | Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera) |
| title_short | Progress on synthesis of benzylisoquinoline alkaloids in sacred lotus (Nelumbo nucifera) |
| title_sort | progress on synthesis of benzylisoquinoline alkaloids in sacred lotus nelumbo nucifera |
| topic | benzylisoquinoline alkaloids nelumbo nucifera sacred lotus biosynthesis |
| url | https://www.maxapress.com/article/doi/10.48130/MPB-2023-0020 |
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