Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases

Osteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and r...

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Bibliographic Details
Main Authors: Saw KY, Jee CSY, Ramlan A, Dawam A, Saw YC, Low SF
Format: Article
Language:English
Published: Malaysian Orthopaedic Association 2022-11-01
Series:Malaysian Orthopaedic Journal
Subjects:
Online Access:http://morthoj.org/2022/v16n3/osteochondral-lesions-talus.pdf
Description
Summary:Osteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and regeneration of the bone and cartilage components. Improvement in Ankle Osteoarthritis Scale (AOS) scores with minimum two years follow-up showed statistical significance (p < 0.05).
ISSN:1985-2533
2232-111X