Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases

Osteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and r...

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Main Authors: Saw KY, Jee CSY, Ramlan A, Dawam A, Saw YC, Low SF
Format: Article
Language:English
Published: Malaysian Orthopaedic Association 2022-11-01
Series:Malaysian Orthopaedic Journal
Subjects:
Online Access:http://morthoj.org/2022/v16n3/osteochondral-lesions-talus.pdf
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author Saw KY
Jee CSY
Ramlan A
Dawam A
Saw YC
Low SF
author_facet Saw KY
Jee CSY
Ramlan A
Dawam A
Saw YC
Low SF
author_sort Saw KY
collection DOAJ
description Osteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and regeneration of the bone and cartilage components. Improvement in Ankle Osteoarthritis Scale (AOS) scores with minimum two years follow-up showed statistical significance (p < 0.05).
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spelling doaj.art-7f01e33f982548fa9c52a520165fc3a52022-12-22T04:42:18ZengMalaysian Orthopaedic AssociationMalaysian Orthopaedic Journal1985-25332232-111X2022-11-0116312813110.5704/MOJ.2211.019Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five CasesSaw KY0Jee CSY 1Ramlan A2Dawam A3Saw YC4Low SF5MCh OrthPhDBScMScGCE AMMed RadOsteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and regeneration of the bone and cartilage components. Improvement in Ankle Osteoarthritis Scale (AOS) scores with minimum two years follow-up showed statistical significance (p < 0.05). http://morthoj.org/2022/v16n3/osteochondral-lesions-talus.pdfosteochondral lesions of the talusankle osteoarthritisosteochondrogenesisperipheral blood stem cellsmarrow stimulation
spellingShingle Saw KY
Jee CSY
Ramlan A
Dawam A
Saw YC
Low SF
Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
Malaysian Orthopaedic Journal
osteochondral lesions of the talus
ankle osteoarthritis
osteochondrogenesis
peripheral blood stem cells
marrow stimulation
title Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_full Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_fullStr Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_full_unstemmed Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_short Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_sort osteochondrogenesis with autologous peripheral blood stem cells for osteochondral lesions of the talus report of five cases
topic osteochondral lesions of the talus
ankle osteoarthritis
osteochondrogenesis
peripheral blood stem cells
marrow stimulation
url http://morthoj.org/2022/v16n3/osteochondral-lesions-talus.pdf
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AT jeecsy osteochondrogenesiswithautologousperipheralbloodstemcellsforosteochondrallesionsofthetalusreportoffivecases
AT ramlana osteochondrogenesiswithautologousperipheralbloodstemcellsforosteochondrallesionsofthetalusreportoffivecases
AT dawama osteochondrogenesiswithautologousperipheralbloodstemcellsforosteochondrallesionsofthetalusreportoffivecases
AT sawyc osteochondrogenesiswithautologousperipheralbloodstemcellsforosteochondrallesionsofthetalusreportoffivecases
AT lowsf osteochondrogenesiswithautologousperipheralbloodstemcellsforosteochondrallesionsofthetalusreportoffivecases