Effect of a retinoic acid analogue on BMP-driven pluripotent stem cell chondrogenesis

Abstract Osteoarthritis is the most common degenerative joint condition, leading to articular cartilage (AC) degradation, chronic pain and immobility. The lack of appropriate therapies that provide tissue restoration combined with the limited lifespan of joint-replacement implants indicate the need...

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Bibliographic Details
Main Authors: Fabrizio E. Mancini, Paul E. A. Humphreys, Steven Woods, Nicola Bates, Sara Cuvertino, Julieta O’Flaherty, Leela Biant, Marco A. N. Domingos, Susan J. Kimber
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-52362-3