Small Heat Shock Proteins in Retinal Diseases
This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Molecular Biosciences |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.860375/full |
| _version_ | 1819023870644977664 |
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| author | Vivian Rajeswaren Jeffrey O. Wong Dana Yabroudi Rooban B. Nahomi Johanna Rankenberg Mi-Hyun Nam Ram H. Nagaraj Ram H. Nagaraj |
| author_facet | Vivian Rajeswaren Jeffrey O. Wong Dana Yabroudi Rooban B. Nahomi Johanna Rankenberg Mi-Hyun Nam Ram H. Nagaraj Ram H. Nagaraj |
| author_sort | Vivian Rajeswaren |
| collection | DOAJ |
| description | This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed. |
| first_indexed | 2024-12-21T04:45:46Z |
| format | Article |
| id | doaj.art-7f07f974e8de494d89f5242ff55631d8 |
| institution | Directory Open Access Journal |
| issn | 2296-889X |
| language | English |
| last_indexed | 2024-12-21T04:45:46Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Molecular Biosciences |
| spelling | doaj.art-7f07f974e8de494d89f5242ff55631d82022-12-21T19:15:35ZengFrontiers Media S.A.Frontiers in Molecular Biosciences2296-889X2022-04-01910.3389/fmolb.2022.860375860375Small Heat Shock Proteins in Retinal DiseasesVivian Rajeswaren0Jeffrey O. Wong1Dana Yabroudi2Rooban B. Nahomi3Johanna Rankenberg4Mi-Hyun Nam5Ram H. Nagaraj6Ram H. Nagaraj7Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, School of Medicine, Aurora, CO, United StatesDepartment of Ophthalmology, Sue Anschutz-Rodgers Eye Center, School of Medicine, Aurora, CO, United StatesDepartment of Ophthalmology, Sue Anschutz-Rodgers Eye Center, School of Medicine, Aurora, CO, United StatesDepartment of Ophthalmology, Sue Anschutz-Rodgers Eye Center, School of Medicine, Aurora, CO, United StatesDepartment of Ophthalmology, Sue Anschutz-Rodgers Eye Center, School of Medicine, Aurora, CO, United StatesDepartment of Ophthalmology, Sue Anschutz-Rodgers Eye Center, School of Medicine, Aurora, CO, United StatesDepartment of Ophthalmology, Sue Anschutz-Rodgers Eye Center, School of Medicine, Aurora, CO, United StatesDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, United StatesThis review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed.https://www.frontiersin.org/articles/10.3389/fmolb.2022.860375/fullsmall heat shock proteinsglaucomadiabetic retinopathyage-related macular degenerationretina |
| spellingShingle | Vivian Rajeswaren Jeffrey O. Wong Dana Yabroudi Rooban B. Nahomi Johanna Rankenberg Mi-Hyun Nam Ram H. Nagaraj Ram H. Nagaraj Small Heat Shock Proteins in Retinal Diseases Frontiers in Molecular Biosciences small heat shock proteins glaucoma diabetic retinopathy age-related macular degeneration retina |
| title | Small Heat Shock Proteins in Retinal Diseases |
| title_full | Small Heat Shock Proteins in Retinal Diseases |
| title_fullStr | Small Heat Shock Proteins in Retinal Diseases |
| title_full_unstemmed | Small Heat Shock Proteins in Retinal Diseases |
| title_short | Small Heat Shock Proteins in Retinal Diseases |
| title_sort | small heat shock proteins in retinal diseases |
| topic | small heat shock proteins glaucoma diabetic retinopathy age-related macular degeneration retina |
| url | https://www.frontiersin.org/articles/10.3389/fmolb.2022.860375/full |
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