A novel recombinant human plasminogen activator: Efficient expression and hereditary stability in transgenic goats and in vitro thrombolytic bioactivity in the milk of transgenic goats.

BACKGROUND:Thromboses is a rapidly growing medical problem worldwide. Low-cost, high-scale production of thrombotic drugs is needed to meet the demand. The production of biomolecules in transgenic animals might help address this issue. To our knowledge, the expression of recombinant human plasminoge...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Zhengyi He, Rui Lu, Ting Zhang, Lei Jiang, Minya Zhou, Daijin Wu, Yong Cheng
Format: Artykuł
Język:English
Wydane: Public Library of Science (PLoS) 2018-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC6097695?pdf=render