A functional promoter polymorphism of IFITM3 is associated with susceptibility to pediatric tuberculosis in Han Chinese population.

A functional promoter polymorphism of IFITM3 is associated with susceptibility to pediatric tuberculosis in Han Chinese population.

A susceptibility locus for tuberculosis, a re-emerging infectious disease throughout the world, was previously discovered to exist on chromosome 11p15. IFITM3 gene encoding for interferon inducible transmembrane protein 3, is located at 11p15. It acts as an effector molecule for interferon-gamma, wh...

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Bibliographic Details
Main Authors: Chen Shen, Xi-rong Wu, Wei-wei Jiao, Lin Sun, Wei-xing Feng, Jing Xiao, Qing Miao, Fang Liu, Qing-qin Yin, Chen-guang Zhang, Ya-jie Guo, A-dong Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3706438?pdf=render

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