Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease

Tuberculosis is one of the most prevalent bacterial infection in developing country like india and it is capable of affecting almost every system in the human body. Multifocal skeletal tuberculosis is a rare condition. We report a 22-year old immunocompetent female history of backache and sterna...

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Main Author: Majed B Momin1 , Sandeep S2 , Anamika Aluri3 , Akhhil M4
Format: Article
Language:English
Published: Prathima Institute of Medical Sciences 2018-08-01
Series:Perspectives In Medical Research
Subjects:
Online Access:http://www.pimr.org.in/majid-vol-6-issue-2-2018.PDF
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author Majed B Momin1 , Sandeep S2 , Anamika Aluri3 , Akhhil M4
author_facet Majed B Momin1 , Sandeep S2 , Anamika Aluri3 , Akhhil M4
author_sort Majed B Momin1 , Sandeep S2 , Anamika Aluri3 , Akhhil M4
collection DOAJ
description Tuberculosis is one of the most prevalent bacterial infection in developing country like india and it is capable of affecting almost every system in the human body. Multifocal skeletal tuberculosis is a rare condition. We report a 22-year old immunocompetent female history of backache and sternal pain for three months, associated with progressive weight loss with no fever. Computed Tomography (CT) scanning demonstrated hypodense multifocal osteolytic lesions of the thoracic spine (T12) and the manubrum sternii. CT guided fine needle aspiration cytology (FNAC) performed from both osteolytic lesions. Cytology smears from both lesions show many granulomas and few giant cells. Z-N stain for AFB was positive. Patient treated with anti-tuberculus drugs and responded well. This case reported for its rarity, unusual radiological findings & to emphasize the role of CT/CT guided FNAC in osteolytic lesions and also to stress the need for high index of suspicion in tuberculosis endemic areas to avoid delayed diagnosis in such uncommon presentation of common disease.
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spelling doaj.art-7f0e82b1a9aa4dc18dc53e5ff0f7fecd2023-11-24T11:52:42ZengPrathima Institute of Medical SciencesPerspectives In Medical Research2348-14472348-229X2018-08-01626971Multifocal Osteolytic tuberculosis - Uncommon presentation of common diseaseMajed B Momin1 , Sandeep S2 , Anamika Aluri3 , Akhhil M40 Yashoda HospitalTuberculosis is one of the most prevalent bacterial infection in developing country like india and it is capable of affecting almost every system in the human body. Multifocal skeletal tuberculosis is a rare condition. We report a 22-year old immunocompetent female history of backache and sternal pain for three months, associated with progressive weight loss with no fever. Computed Tomography (CT) scanning demonstrated hypodense multifocal osteolytic lesions of the thoracic spine (T12) and the manubrum sternii. CT guided fine needle aspiration cytology (FNAC) performed from both osteolytic lesions. Cytology smears from both lesions show many granulomas and few giant cells. Z-N stain for AFB was positive. Patient treated with anti-tuberculus drugs and responded well. This case reported for its rarity, unusual radiological findings & to emphasize the role of CT/CT guided FNAC in osteolytic lesions and also to stress the need for high index of suspicion in tuberculosis endemic areas to avoid delayed diagnosis in such uncommon presentation of common disease.http://www.pimr.org.in/majid-vol-6-issue-2-2018.PDFtuberculosisimmunocompetentosteolytic lesionsthoracic spine (t12)
spellingShingle Majed B Momin1 , Sandeep S2 , Anamika Aluri3 , Akhhil M4
Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease
Perspectives In Medical Research
tuberculosis
immunocompetent
osteolytic lesions
thoracic spine (t12)
title Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease
title_full Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease
title_fullStr Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease
title_full_unstemmed Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease
title_short Multifocal Osteolytic tuberculosis - Uncommon presentation of common disease
title_sort multifocal osteolytic tuberculosis uncommon presentation of common disease
topic tuberculosis
immunocompetent
osteolytic lesions
thoracic spine (t12)
url http://www.pimr.org.in/majid-vol-6-issue-2-2018.PDF
work_keys_str_mv AT majedbmomin1sandeeps2anamikaaluri3akhhilm4 multifocalosteolytictuberculosisuncommonpresentationofcommondisease