Epstein-Barr Virus Coinfection in COVID-19

Epstein-Barr virus (EBV), a member of the herpes virus family, is a causative agent for infectious mononucleosis in young adults. It has an asymptomatic and subclinical distribution in about 90% to 95% of the world population based on seropositivity. EBV is associated with various lymphomas, nasopha...

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Main Authors: Asim Nadeem MD, Krithika Suresh MD, Hassan Awais MD, Saba Waseem MD
Format: Article
Language:English
Published: SAGE Publishing 2021-08-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/23247096211040626
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author Asim Nadeem MD
Krithika Suresh MD
Hassan Awais MD
Saba Waseem MD
author_facet Asim Nadeem MD
Krithika Suresh MD
Hassan Awais MD
Saba Waseem MD
author_sort Asim Nadeem MD
collection DOAJ
description Epstein-Barr virus (EBV), a member of the herpes virus family, is a causative agent for infectious mononucleosis in young adults. It has an asymptomatic and subclinical distribution in about 90% to 95% of the world population based on seropositivity. EBV is associated with various lymphomas, nasopharyngeal carcinoma, and in immunocompromised states can give rise to aggressive lymphoproliferative disorders. Symptomatic patients mostly present with mild hepatitis, rash, oral symptoms, lymphadenopathy, and generalized malaise. Recently with the COVID-19 (coronavirus disease-2019) pandemic, hepatitis has been found to be related to acute EBV and cytomegalovirus reactivation versus acute infection in the absence of other major causes. We describe a case of EBV coinfection in a patient with resolving mild COVID-19 infection.
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spelling doaj.art-7f0eb288a1904e9a808c2aed7d81e0962022-12-21T21:35:52ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962021-08-01910.1177/23247096211040626Epstein-Barr Virus Coinfection in COVID-19Asim Nadeem MD0Krithika Suresh MD1Hassan Awais MD2Saba Waseem MD3Conemaugh Memorial Medical Center, Johnstown, PA, USAConemaugh Memorial Medical Center, Johnstown, PA, USAConemaugh Memorial Medical Center, Johnstown, PA, USAConemaugh Memorial Medical Center, Johnstown, PA, USAEpstein-Barr virus (EBV), a member of the herpes virus family, is a causative agent for infectious mononucleosis in young adults. It has an asymptomatic and subclinical distribution in about 90% to 95% of the world population based on seropositivity. EBV is associated with various lymphomas, nasopharyngeal carcinoma, and in immunocompromised states can give rise to aggressive lymphoproliferative disorders. Symptomatic patients mostly present with mild hepatitis, rash, oral symptoms, lymphadenopathy, and generalized malaise. Recently with the COVID-19 (coronavirus disease-2019) pandemic, hepatitis has been found to be related to acute EBV and cytomegalovirus reactivation versus acute infection in the absence of other major causes. We describe a case of EBV coinfection in a patient with resolving mild COVID-19 infection.https://doi.org/10.1177/23247096211040626
spellingShingle Asim Nadeem MD
Krithika Suresh MD
Hassan Awais MD
Saba Waseem MD
Epstein-Barr Virus Coinfection in COVID-19
Journal of Investigative Medicine High Impact Case Reports
title Epstein-Barr Virus Coinfection in COVID-19
title_full Epstein-Barr Virus Coinfection in COVID-19
title_fullStr Epstein-Barr Virus Coinfection in COVID-19
title_full_unstemmed Epstein-Barr Virus Coinfection in COVID-19
title_short Epstein-Barr Virus Coinfection in COVID-19
title_sort epstein barr virus coinfection in covid 19
url https://doi.org/10.1177/23247096211040626
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