Dual Versus Single Oxygenated Hypothermic Machine Perfusion of Porcine Livers: Impact on Hepatobiliary and Endothelial Cell Injury

Dual Versus Single Oxygenated Hypothermic Machine Perfusion of Porcine Livers: Impact on Hepatobiliary and Endothelial Cell Injury

Background. Hypothermic oxygenated machine perfusion (HOPE) reduces ischemia-reperfusion injury of donor livers and is increasingly used in clinical transplantation. However, it remains unclear whether perfusion via the portal vein alone (HOPE) or via both the portal vein and hepatic artery (dual HO...

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Main Authors: Yvonne de Vries, MD, PhD, Isabel M. A. Brüggenwirth, BSc, Shanice A. Karangwa, MD, Fien A. von Meijenfeldt, BSc, Otto B. van Leeuwen, PhD, Laura C. Burlage, MD, PhD, Iris E. M. de Jong, MD, Annette S. H. Gouw, MD, PhD, Vincent E. de Meijer, MD, PhD, Ton Lisman, PhD, Robert J. Porte, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2021-09-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001184

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